Imipenem and cilastatin and Dexamethasone sodium phosphate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imipenem and cilastatin (cilastatin sodium; imipenem) and Dexamethasone sodium phosphate (dexamethasone sodium phosphate). Common drug interactions include pneumonia among females and myelosuppression among males.

The phase IV clinical study analyzes what interactions people have when they take Imipenem and cilastatin and Dexamethasone sodium phosphate. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Imipenem and cilastatin?

Imipenem and cilastatin has active ingredients of cilastatin sodium; imipenem. eHealthMe is studying from 2,097 Imipenem and cilastatin users. Check the latest studies of Imipenem and cilastatin.

What is Dexamethasone sodium phosphate?

Dexamethasone sodium phosphate has active ingredients of dexamethasone sodium phosphate. It is often used in multiple myeloma. eHealthMe is studying from 12,101 Dexamethasone sodium phosphate users. Check the latest studies of Dexamethasone sodium phosphate.



On Jul, 07, 2026

54 people who take Imipenem and cilastatin and Dexamethasone sodium phosphate together, and have interactions are studied.

Imipenem and cilastatin and Dexamethasone sodium phosphate drug interactions.

What are the common drug interactions of Imipenem And Cilastatin and Dexamethasone Sodium Phosphate, by gender? *:

female:

  1. Pneumonia
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Interstitial lung disease
  5. Granulocytosis (the presence in peripheral blood of an increased number of granulocytes)
  6. Platelet count decreased
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Enteritis (inflammation of the small intestine)
  9. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  10. Myocarditis (inflammation of heart muscle myocardium)

male:

  1. Myelosuppression (a decrease in the production of blood cells)
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Pneumonia fungal
  4. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  5. Ileus (a painful obstruction of the ileum or other part of the intestine)
  6. Lymphocytic hypophysitis (inflammation of the pituitary gland)
  7. Fatigue (feeling of tiredness)
  8. Leukopenia (less number of white blood cells in blood)
  9. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  10. Hyperthyroidism (over activity of the thyroid gland)

What are the common drug interactions of Imipenem And Cilastatin and Dexamethasone Sodium Phosphate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Erythropenia (a deficiency in the number of red blood cells)
  2. Granulocytopenia (lack of granulocyte)
  3. Thrombocytopenia (decrease of platelets in blood)

10-19:

  1. Neutropenic infection (infection with less neutrophil numbers in blood)
  2. Acute lymphocytic leukaemia (cancer of the white blood cells)
  3. Haemorrhage (bleeding)

20-29:

n/a

30-39:

  1. Large intestine perforation (hole in large intestine)
  2. Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Small intestinal haemorrhage (bleeding from small intestine)

40-49:

n/a

50-59:

  1. Pneumonia
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Anaemia (lack of blood)
  4. Myelosuppression (a decrease in the production of blood cells)
  5. Ileus (a painful obstruction of the ileum or other part of the intestine)
  6. Lymphocytic hypophysitis (inflammation of the pituitary gland)
  7. Platelet count decreased
  8. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  9. Sepsis (a severe blood infection that can lead to organ failure and death)
  10. Back pain

60+:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Fatigue (feeling of tiredness)
  4. Interstitial lung disease
  5. Leukopenia (less number of white blood cells in blood)
  6. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  7. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  8. Granulocytosis (the presence in peripheral blood of an increased number of granulocytes)
  9. Hyperthyroidism (over activity of the thyroid gland)
  10. Cardiac arrest

What are the existing conditions these people have? *

  1. Constipation: 21 people, 38.89%
  2. Urination - Excessive Volume: 19 people, 35.19%
  3. Anaemia (lack of blood): 17 people, 31.48%
  4. Fever: 17 people, 31.48%
  5. Hypokalemia (low potassium): 15 people, 27.78%
  6. Productive Cough: 11 people, 20.37%
  7. Nausea And Vomiting: 11 people, 20.37%
  8. Blood Glucose Decreased: 10 people, 18.52%
  9. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 10 people, 18.52%
  10. Hypocalcaemia (levels of calcium in blood serum are abnormally low): 10 people, 18.52%

* Approximation only. Some reports may have incomplete information.

Do you take Imipenem and cilastatin and Dexamethasone sodium phosphate?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Imipenem and cilastatin and Dexamethasone sodium phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imipenem and cilastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dexamethasone sodium phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imipenem and cilastatin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dexamethasone sodium phosphate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cilastatin sodium; imipenem and dexamethasone sodium phosphate (the active ingredients of Imipenem and cilastatin and Dexamethasone sodium phosphate, respectively), and Imipenem and cilastatin and Dexamethasone sodium phosphate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: