Imipramine hydrochloride and Losartan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Imipramine hydrochloride (imipramine hydrochloride) and Losartan (losartan potassium). Common drug interactions include asthenia among females and muscle spasms among males.
The phase IV clinical study analyzes what interactions people have when they take Imipramine hydrochloride and Losartan. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Imipramine hydrochloride?
Imipramine hydrochloride has active ingredients of imipramine hydrochloride. It is often used in depression. eHealthMe is studying from 920 Imipramine hydrochloride users. Check the latest studies of Imipramine hydrochloride.
What is Losartan?
Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,686 Losartan users. Check the latest studies of Losartan.
22 people who take Imipramine hydrochloride and Losartan together, and have interactions are studied.

What are the common drug interactions of Imipramine Hydrochloride and Losartan, by gender? *:
female:
- Asthenia (weakness)
- Infection
- Sinusitis (inflammation of sinus)
- Insomnia (sleeplessness)
- Nausea (feeling of having an urge to vomit)
- Urinary tract infection
- Alopecia (absence of hair from areas of the body)
- Blood potassium decreased
- Blood thyroid stimulating hormone increased
- Confusional state
male:
- Muscle spasms (muscle contraction)
- Therapeutic response unexpected
- Blood triglycerides increased
- Cardiac failure congestive
- Cardiomyopathy (weakening of the heart muscle)
- Cardiovascular disorder (heart diseases)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Death
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dyspepsia (indigestion)
What are the common drug interactions of Imipramine Hydrochloride and Losartan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
- Contusion (a type of hematoma of tissue in which capillaries)
- Facial bones fracture (bone fracture of face)
- Fall
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Nausea (feeling of having an urge to vomit)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Urinary tract infection
50-59:
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Influenza
- Infusion related reaction
- Nausea (feeling of having an urge to vomit)
- Rectal prolapse (falling of rectum from normal place)
- Sinusitis (inflammation of sinus)
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Upper respiratory tract infection
- Arrhythmia (irregular heartbeat)
60+:
- Asthenia (weakness)
- Infection
- Eyelid irritation
- Incoherent (talking in a confused and unclear way)
- Malaise (a feeling of general discomfort or uneasiness)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Pain in extremity
- Poor peripheral circulation
- Sinusitis (inflammation of sinus)
- Urinary tract infection
What are the existing conditions these people have? *
- Cardiac Disorder: 3 people, 13.64%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 13.64%
- Diabetes: 3 people, 13.64%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 13.64%
- Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 9.09%
- High Blood Cholesterol: 2 people, 9.09%
- Drowsiness: 2 people, 9.09%
- Gastric Disorder (disease of stomach): 2 people, 9.09%
- Gastritis (inflammation of stomach): 2 people, 9.09%
- Immunodeficiency Common Variable: 2 people, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Imipramine hydrochloride and Losartan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Imipramine hydrochloride (920 reports)
- Losartan (177,686 reports)
Browse all drug interactions of Imipramine hydrochloride and Losartan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Imipramine hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Losartan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Imipramine hydrochloride and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Losartan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on imipramine hydrochloride and losartan potassium (the active ingredients of Imipramine hydrochloride and Losartan, respectively), and Imipramine hydrochloride and Losartan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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