Imitrex and Accolate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imitrex (sumatriptan succinate) and Accolate (zafirlukast). Common drug interactions include headache among females.

The phase IV clinical study analyzes what interactions people have when they take Imitrex and Accolate. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Imitrex?

Imitrex has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 17,149 Imitrex users. Check the latest studies of Imitrex.

What is Accolate?

Accolate has active ingredients of zafirlukast. It is often used in asthma. eHealthMe is studying from 4,220 Accolate users. Check the latest studies of Accolate.

On Aug, 02, 2026

24 people who take Imitrex and Accolate together, and have interactions are studied.

What are the common drug interactions of Imitrex and Accolate, by gender? *:

female:

Headache (pain in head)
Anaphylactic reaction (serious allergic reaction)
Abdominal pain
Abdominal tenderness
Abnormal behaviour
Accident
Alopecia (absence of hair from areas of the body)
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Blood cholesterol increased
Blood glucose decreased

male:

n/a

What are the common drug interactions of Imitrex and Accolate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anaphylactic reaction (serious allergic reaction)
Dyspnoea (difficult or laboured respiration)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Injection site urticaria (rash of round, red welts on the skin at injection site)
Syncope (loss of consciousness with an inability to maintain postural tone)
Abnormal behaviour
Anxiety
Blood pressure decreased
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression

40-49:

Abdominal pain
Accident
Alopecia (absence of hair from areas of the body)
Anxiety
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Blood cholesterol increased
Blood triglycerides increased
Chest pain
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery spasm

50-59:

Duodenitis (inflammation of the duodenum)
Gastritis (inflammation of stomach)
Haematocrit decreased
Headache (pain in head)
Melaena (the passage of black, tarry stools)
Pain in extremity
Rectal bleeding (bleeding from rectum)
Throat tightness
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Vertigo

60+:

Blood glucose decreased
Blood glucose increased
Contusion (a type of hematoma of tissue in which capillaries)
Dizziness
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Insomnia (sleeplessness)

What are the existing conditions these people have? *

Sleep Disorder: 2 people, 8.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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