Imitrex and Humalog drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imitrex (sumatriptan succinate) and Humalog (insulin lispro recombinant). Common drug interactions include fall among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Imitrex and Humalog. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Imitrex?

Imitrex has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 17,149 Imitrex users. Check the latest studies of Imitrex.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.

On Jul, 30, 2026

46 people who take Imitrex and Humalog together, and have interactions are studied.

What are the common drug interactions of Imitrex and Humalog, by gender? *:

female:

Fall
Injury
Intervertebral disc protrusion (spinal disc protrusion)
Nephrolithiasis (calculi in the kidneys)
Neuropathy peripheral (surface nerve damage)
Oedema peripheral (superficial swelling)
Rash
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Upper limb fracture
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

male:

Chest pain
Anxiety
Asthenia (weakness)
Axonal neuropathy (dysfunction of axon nerves)
Back disorder
Blindness
Blood glucose decreased
Blood triglycerides increased
Bradycardia (abnormally slow heart action)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

What are the common drug interactions of Imitrex and Humalog, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Hyperglycaemia (high blood sugar)
Vomiting

20-29:

Cholecystitis acute (rapid infection of gallbladder)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Drug exposure during pregnancy
Gallbladder disorder
Loss of consciousness
Pain

30-39:

Dyspnoea (difficult or laboured respiration)
Syncope (loss of consciousness with an inability to maintain postural tone)
Abdominal pain
Anaphylactic reaction (serious allergic reaction)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Injection site urticaria (rash of round, red welts on the skin at injection site)
Blood glucose increased
Colitis (inflammation of colon)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Injury

40-49:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Depression
Pain
Pneumonia
Anxiety
Cardiac murmur (an heart sound in valve abnormality)
Cellulitis (infection under the skin)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diabetic ulcer

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthropathy
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Bipolar disorder (mood disorder)
Blood cholesterol increased
Calculus bladder (bladder stone)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)

60+:

Anxiety
Anaemia (lack of blood)
Diabetes mellitus inadequate control
Dyspnoea (difficult or laboured respiration)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Hypertension (high blood pressure)
Impaired work ability
Intervertebral disc protrusion (spinal disc protrusion)
Muscular weakness (muscle weakness)
Neuropathy peripheral (surface nerve damage)

What are the existing conditions these people have? *

Depression: 10 people, 21.74%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 17.39%
High Blood Cholesterol: 6 people, 13.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 13.04%
Headache (pain in head): 6 people, 13.04%
Pain: 5 people, 10.87%
Type 2 Diabetes: 3 people, 6.52%
Asthma: 3 people, 6.52%
Bipolar Disorder (mood disorder): 3 people, 6.52%
Heart Rate Irregular: 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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