Imitrex and Methylprednisolone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imitrex (sumatriptan succinate) and Methylprednisolone (methylprednisolone). Common drug interactions include breast abscess among females and cerebral ischaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Imitrex and Methylprednisolone. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Imitrex?

Imitrex has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 17,149 Imitrex users. Check the latest studies of Imitrex.

What is Methylprednisolone?

Methylprednisolone has active ingredients of methylprednisolone. It is often used in inflammation. eHealthMe is studying from 59,645 Methylprednisolone users. Check the latest studies of Methylprednisolone.

On Jul, 27, 2026

63 people who take Imitrex and Methylprednisolone together, and have interactions are studied.

Imitrex and Methylprednisolone drug interactions.

What are the common drug interactions of Imitrex and Methylprednisolone, by gender? *:

female:

Breast abscess
Breast cellulitis (spreading, acute inflammation of beast skin)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiovascular disorder (heart diseases)
Cerebral thrombosis (blood clot in brain)
Cholecystitis (infection of gallbladder)
Cholecystitis chronic (long lasting infection of gallbladder)
Decreased appetite
Dependence
Diarrhoea haemorrhagic (bloody diarrhoea)

male:

Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Drug addiction
Drug screen positive
Dyspnoea (difficult or laboured respiration)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Imitrex and Methylprednisolone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)
Injury
Anxiety
Cerebral thrombosis (blood clot in brain)
Cholecystitis (infection of gallbladder)
Emotional distress
Headache (pain in head)
Abdominal pain

30-39:

Acne (skin problems that cause pimples)
Asthenia (weakness)
Back pain
Burning sensation
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Heart rate decreased
Influenza

40-49:

Patellofemoral pain syndrome (pain in the front of the knee)
Polydipsia (excessive thirst)
Polyuria (production of too much dilute urine)
Psychomotor skills impaired
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Temperature intolerance (inability to go in temperature)
Thyroid neoplasm (tumour of thyroid)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Weight increased
Abdominal pain lower

50-59:

Foot fracture
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Pain in extremity
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Aspartate aminotransferase increased
Blood creatinine increased

60+:

Anxiety
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Gallbladder disorder
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
General physical health deterioration (weak health status)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Injury
Nausea (feeling of having an urge to vomit)
Night sweats (sweating in night)

What are the existing conditions these people have? *

Pain: 18 people, 28.57%
Muscle Spasms (muscle contraction): 18 people, 28.57%
Depression: 18 people, 28.57%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 14 people, 22.22%
Nausea (feeling of having an urge to vomit): 13 people, 20.63%
Headache (pain in head): 12 people, 19.05%
Sleep Disorder: 11 people, 17.46%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 11 people, 17.46%
Birth Control: 9 people, 14.29%
Premenstrual Syndrome: 8 people, 12.70%

* Approximation only. Some reports may have incomplete information.

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