Imodium a-d and Ms contin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium a-d (loperamide hydrochloride) and Ms contin (morphine sulfate). Common drug interactions include chest discomfort among females and hyponatraemia among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium a-d and Ms contin. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium a-d?

Imodium a-d has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 8,944 Imodium a-d users. Check the latest studies of Imodium a-d.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.



On Jul, 19, 2026

32 people who take Imodium a-d and Ms contin together, and have interactions are studied.

Imodium a-d and Ms contin drug interactions.

What are the common drug interactions of Imodium A-D and Ms Contin, by gender? *:

female:

  1. Chest discomfort
  2. Death
  3. Decreased appetite
  4. Dehydration (dryness resulting from the removal of water)
  5. Depression
  6. Dyspepsia (indigestion)
  7. Fall
  8. Hypotension (abnormally low blood pressure)
  9. Myalgia (muscle pain)
  10. Pneumonia

male:

  1. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  2. Pericardial effusion (fluid around the heart)
  3. Abdominal pain
  4. Anxiety
  5. Arthralgia (joint pain)
  6. Atelectasis (partial or complete collapse of the lung)
  7. Blood magnesium decreased
  8. Blood sodium decreased
  9. Bone disorder
  10. Bone marrow disorder

What are the common drug interactions of Imodium A-D and Ms Contin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal discomfort
  2. Abdominal distension
  3. Anaemia (lack of blood)
  4. Anxiety
  5. Arthralgia (joint pain)
  6. Asthenia (weakness)
  7. Atelectasis (partial or complete collapse of the lung)
  8. Blood magnesium decreased
  9. Blood sodium decreased
  10. Bone disorder

50-59:

  1. White blood cell count decreased
  2. Anaemia (lack of blood)
  3. Constipation
  4. Decreased appetite
  5. Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
  6. Encephalopathy (functioning of the brain is affected by some agent or condition)
  7. Hepatic mass
  8. Hypophagia (reduced food intake)
  9. Hypovolaemia (a decreased volume of circulating blood in the body)
  10. Lung adenocarcinoma (a form of non-small cell lung cancer)

60+:

  1. Anaemia (lack of blood)
  2. Dehydration (dryness resulting from the removal of water)
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Hypotension (abnormally low blood pressure)
  5. Myalgia (muscle pain)
  6. Pneumonia
  7. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  8. Rash
  9. Sepsis (a severe blood infection that can lead to organ failure and death)
  10. Stomatitis (inflammation of mucous membrane of mouth)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 9 people, 28.12%
  2. Constipation: 9 people, 28.12%
  3. Thyroid Cancer Metastatic (thyroid cancer spreads to other part): 7 people, 21.88%
  4. Blood Pressure Abnormal: 7 people, 21.88%
  5. Nausea (feeling of having an urge to vomit): 5 people, 15.62%
  6. Renal Cell Carcinoma (a kidney cancer): 2 people, 6.25%
  7. Cough: 2 people, 6.25%
  8. Colon Cancer: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Imodium a-d and Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imodium a-d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imodium a-d and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ms contin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride and morphine sulfate (the active ingredients of Imodium a-d and Ms contin, respectively), and Imodium a-d and Ms contin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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