Imodium and Atacand drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Atacand (candesartan cilexetil). Common drug interactions include neutropenia among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Atacand. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Atacand?

Atacand has active ingredients of candesartan cilexetil. It is often used in high blood pressure. eHealthMe is studying from 22,473 Atacand users. Check the latest studies of Atacand.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

98 people who take Imodium and Atacand together, and have interactions are studied.

What are the common drug interactions of Imodium and Atacand, by gender? *:

female:

Neutropenia (an abnormally low number of neutrophils)
Mucosal inflammation (infection of mucous membrane)
Pyrexia (fever)
Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Eating disorder
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic kidney disease
Loss of consciousness

male:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Fatigue (feeling of tiredness)
Alanine aminotransferase increased
Animal scratch
Arthralgia (joint pain)
Asthenia (weakness)
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
Cellulitis (infection under the skin)
Escherichia sepsis (bacterial infection by escherichia coli)

What are the common drug interactions of Imodium and Atacand, by age (0-1 to 60+)? *:

0-1:

Hyperkalaemia (damage to or disease of the kidney)
Syncope (loss of consciousness with an inability to maintain postural tone)

2-9:

n/a

10-19:

n/a

20-29:

Cholecystitis chronic (long lasting infection of gallbladder)
Hypokalaemia (low potassium)
Injury
Neutropenia (an abnormally low number of neutrophils)
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Drug intolerance (drug sensitivity)

30-39:

n/a

40-49:

Pain in jaw

50-59:

Haemoglobin decreased
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombosis (formation of a blood clot inside a blood vessel)
White blood cell count decreased
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Mixed liver injury
Colitis (inflammation of colon)
Contusion (a type of hematoma of tissue in which capillaries)

60+:

Hypokalaemia (low potassium)
Febrile neutropenia (fever with reduced white blood cells)
Weight decreased
Nausea (feeling of having an urge to vomit)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Renal failure (kidney dysfunction)
Abdominal pain upper
Eating disorder
Animal scratch

What are the existing conditions these people have? *

Pain: 14 people, 14.29%
Indigestion: 14 people, 14.29%
Nausea (feeling of having an urge to vomit): 13 people, 13.27%
Metastatic Gastric Cancer (cancer types can spread to the stomach from other place): 13 people, 13.27%
Multiple Myeloma (cancer of the plasma cells): 11 people, 11.22%
Anaemia (lack of blood): 10 people, 10.20%
Headache (pain in head): 10 people, 10.20%
Constipation: 9 people, 9.18%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 9 people, 9.18%
Diabetes: 9 people, 9.18%

* Approximation only. Some reports may have incomplete information.

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