Imodium and Azactam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Azactam (aztreonam). Common drug interactions include hypomagnesaemia among females and apnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Azactam. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Azactam?

Azactam has active ingredients of aztreonam. eHealthMe is studying from 1,044 Azactam users. Check the latest studies of Azactam.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

11 people who take Imodium and Azactam together, and have interactions are studied.

What are the common drug interactions of Imodium and Azactam, by gender? *:

female:

Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
Ventricular fibrillation (abnormally irregular heart rhythm)
Hepatobiliary disease (diseases affect the liver and/or biliary tract)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Neutropenia (an abnormally low number of neutrophils)
Colitis (inflammation of colon)
Rash

male:

Apnoea (suspension of external breathing)
Blood creatinine increased
Urinary retention (the inability to completely or partially empty the bladder)
Blood urea increased
Cardiac disorder
Dysphagia (a condition in which swallowing is difficult or painful)
Generalised oedema (swelling all over the body)
Neutropenia (an abnormally low number of neutrophils)
Pulse absent
Pyrexia (fever)

What are the common drug interactions of Imodium and Azactam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hepatobiliary disease (diseases affect the liver and/or biliary tract)

30-39:

n/a

40-49:

n/a

50-59:

Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
Ventricular fibrillation (abnormally irregular heart rhythm)

60+:

Neutropenia (an abnormally low number of neutrophils)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Pulse absent
Pyrexia (fever)
Sudden death
Urinary retention (the inability to completely or partially empty the bladder)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Apnoea (suspension of external breathing)
Blood creatinine increased
Blood urea increased

What are the existing conditions these people have? *

Constipation: 4 people, 36.36%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 36.36%
Nausea (feeling of having an urge to vomit): 4 people, 36.36%
Fever: 4 people, 36.36%
White Blood Cell Disorder: 2 people, 18.18%
Febrile Neutropenia (fever with reduced white blood cells): 2 people, 18.18%
Hyperglycemia (high blood sugar): 2 people, 18.18%
Human Herpesvirus 6 Infection: 2 people, 18.18%
High Blood Pressure: 2 people, 18.18%
Herpes Simplex (herpes simplex is a common viral infection): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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