Imodium and Clindamycin phosphate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Clindamycin phosphate (clindamycin phosphate). Common drug interactions include malaise among females and chills among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Clindamycin phosphate. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Clindamycin phosphate?

Clindamycin phosphate has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 4,216 Clindamycin phosphate users. Check the latest studies of Clindamycin phosphate.

On Jul, 12, 2026

41 people who take Imodium and Clindamycin phosphate together, and have interactions are studied.

Imodium and Clindamycin phosphate drug interactions.

What are the common drug interactions of Imodium and Clindamycin Phosphate, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pain
Pneumonia
Rash
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Sinusitis (inflammation of sinus)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Stomatitis (inflammation of mucous membrane of mouth)
Thrombocytopenia (decrease of platelets in blood)

male:

Chills (felling of cold)
Decreased appetite
Blood sodium decreased
Body temperature increased
Cardiac failure congestive
Chest pain
Coccydynia (pain in the coccyx or tailbone area)
Death
Dehydration (dryness resulting from the removal of water)
Disease progression

What are the common drug interactions of Imodium and Clindamycin Phosphate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs)
Lip disorder (disease of lip)
Mucosal erosion (peeling off of mucous membrane)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Acute circulatory failure (shock)
Cardiac failure

40-49:

Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
Febrile neutropenia (fever with reduced white blood cells)

50-59:

Lung adenocarcinoma stage iv (the cancer has spread to other organs of the body, such as the other lung, brain, or liver)

60+:

Dehydration (dryness resulting from the removal of water)
Skin disorder (skin disease)
Constipation
Pain in extremity
Activated partial thromboplastin time prolonged
Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
B-cell lymphoma (blood cancer affecting b cells)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood bilirubin increased

What are the existing conditions these people have? *

Anaesthesia: 7 people, 17.07%
Insomnia (sleeplessness): 5 people, 12.20%
Renal Cell Carcinoma (a kidney cancer): 4 people, 9.76%
Non-Small Cell Lung Cancer Stage Iii: 4 people, 9.76%
K-Ras Gene Mutation: 4 people, 9.76%

* Approximation only. Some reports may have incomplete information.

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