Imodium and Daliresp drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Daliresp (roflumilast). Common drug interactions include pollakiuria among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Daliresp. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Daliresp?

Daliresp has active ingredients of roflumilast. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 4,722 Daliresp users. Check the latest studies of Daliresp.

On Aug, 10, 2026

13 people who take Imodium and Daliresp together, and have interactions are studied.

What are the common drug interactions of Imodium and Daliresp, by gender? *:

female:

Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Weight decreased
Abdominal pain upper
Body height decreased
Hypoacusis (loss of hearing)
Malaise (a feeling of general discomfort or uneasiness)
Pneumonia
Psoriasis (immune-mediated disease that affects the skin)
Abdominal pain
Asthenia (weakness)

male:

Abdominal discomfort
Adenoma benign (non-cancerous tumour -secreting)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
B-cell lymphoma (blood cancer affecting b cells)
Cardiomyopathy (weakening of the heart muscle)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Confusional state
Decreased appetite
Fall

What are the common drug interactions of Imodium and Daliresp, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Fall
Abdominal discomfort
Gastric haemorrhage (bleeding stomach)
Hypoacusis (loss of hearing)
Intestinal polyp (small growths in the bowel with the potential for further growth)
Malaise (a feeling of general discomfort or uneasiness)
Pneumonia
Polyp
Psoriasis (immune-mediated disease that affects the skin)
Abdominal pain

What are the existing conditions these people have? *

High Blood Pressure: 2 people, 15.38%
High Blood Cholesterol: 2 people, 15.38%
Asthma: 2 people, 15.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 15.38%
Multiple Myeloma (cancer of the plasma cells): 2 people, 15.38%
Diabetes: 1 person, 7.69%
Heart Attack: 1 person, 7.69%
Gastric Disorder (disease of stomach): 1 person, 7.69%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 7.69%
Fever: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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