Imodium and Nintedanib drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Nintedanib (nintedanib). Common drug interactions include asthenia among females and clostridium difficile colitis among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Nintedanib. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Nintedanib?

Nintedanib has active ingredients of nintedanib. eHealthMe is studying from 1,514 Nintedanib users. Check the latest studies of Nintedanib.



On Jul, 13, 2026

11 people who take Imodium and Nintedanib together, and have interactions are studied.

Imodium and Nintedanib drug interactions.

What are the common drug interactions of Imodium and Nintedanib, by gender? *:

female:

  1. Asthenia (weakness)
  2. Atrial thrombosis (blood clot that develops in an artery)
  3. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  4. Headache (pain in head)
  5. Hypertension (high blood pressure)
  6. Interstitial lung disease
  7. Vomiting
  8. Chest discomfort
  9. Choking sensation (feeling of obstruction in respiratory system)
  10. Cough

male:

  1. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  2. Neck pain
  3. Pneumonia
  4. Cardiac arrest
  5. Constipation

What are the common drug interactions of Imodium and Nintedanib, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Atrial thrombosis (blood clot that develops in an artery)
  2. Headache (pain in head)
  3. Hypertension (high blood pressure)
  4. Vomiting

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Clostridium colitis (inflammation of colon by clostridium difficile bacteria infection)
  2. Blindness unilateral
  3. Pneumonia
  4. Cardiac arrest
  5. Chest discomfort
  6. Choking sensation (feeling of obstruction in respiratory system)
  7. Constipation
  8. Cough
  9. Dyspnoea (difficult or laboured respiration)
  10. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Systemic Sclerosis Pulmonary (an autoimmune or connective tissue disease. it is characterized by thickening of the skin with involvement of lungs): 3 people, 27.27%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 27.27%
  3. Upper Respiratory Tract Infection: 3 people, 27.27%
  4. Weight Decreased: 2 people, 18.18%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 18.18%
  6. Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 18.18%
  7. Lung Cancer - Non-Small Cell (lung cancer): 2 people, 18.18%
  8. Interstitial Lung Disease: 2 people, 18.18%
  9. Indigestion: 1 person, 9.09%
  10. Depression: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Imodium and Nintedanib?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Imodium and Nintedanib:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nintedanib:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nintedanib and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride and nintedanib (the active ingredients of Imodium and Nintedanib, respectively), and Imodium and Nintedanib (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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