Imodium and Serevent drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Serevent (salmeterol xinafoate). Common drug interactions include muscle spasms among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Serevent. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Serevent?

Serevent has active ingredients of salmeterol xinafoate. It is often used in asthma. eHealthMe is studying from 15,586 Serevent users. Check the latest studies of Serevent.

On Aug, 09, 2026

67 people who take Imodium and Serevent together, and have interactions are studied.

What are the common drug interactions of Imodium and Serevent, by gender? *:

female:

Muscle spasms (muscle contraction)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pneumonia
Pyrexia (fever)
Staphylococcal infection (an infection with staphylococcus bacteria)
Urinary tract infection
Abdominal pain
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Adrenal suppression (suppression of cortisol secretion by the adrenal glands)
Anaemia of malignant disease

male:

Chest pain
Fatigue (feeling of tiredness)
Hypokalaemia (low potassium)
Myalgia (muscle pain)
Osteomyelitis (infection of bone)
Palpitations (feelings or sensations that your heart is pounding or racing)
Sinusitis (inflammation of sinus)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Asthenia (weakness)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the common drug interactions of Imodium and Serevent, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Pancreatitis (inflammation of pancreas)
Drug effect decreased
Dyspnoea (difficult or laboured respiration)
Eye irritation
Influenza like illness
Nausea (feeling of having an urge to vomit)
Oedema lower limb (fluid collection in tissue of lower leg)
Oedema upper limb (swelling of arm)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pulmonary congestion (congestion in the lungs)

40-49:

Fatigue (feeling of tiredness)
Somnolence (a state of near-sleep, a strong desire for sleep)

50-59:

Arthralgia (joint pain)
Diabetes mellitus inadequate control
Myalgia (muscle pain)
Neutropenia (an abnormally low number of neutrophils)
Weight decreased
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Anxiety
Aphasia (damage to the parts of the brain that control language)
Arteriovenous malformation
Asthenia (weakness)

60+:

Dyspnoea (difficult or laboured respiration)
Chest pain
Palpitations (feelings or sensations that your heart is pounding or racing)
Renal failure (kidney dysfunction)
Weight increased
Abdominal pain
Antinuclear antibody positive
Anxiety
Asthenia (weakness)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 10 people, 14.93%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 8.96%
High Blood Pressure: 5 people, 7.46%

* Approximation only. Some reports may have incomplete information.

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