Imodium and Tradjenta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Tradjenta (linagliptin). Common drug interactions include ischaemia among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Tradjenta. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Tradjenta?

Tradjenta has active ingredients of linagliptin. It is often used in diabetes. eHealthMe is studying from 9,987 Tradjenta users. Check the latest studies of Tradjenta.

On Jul, 19, 2026

54 people who take Imodium and Tradjenta together, and have interactions are studied.

Imodium and Tradjenta drug interactions.

What are the common drug interactions of Imodium and Tradjenta, by gender? *:

female:

Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Peripheral ischaemia (impaired circulation to an extremity)
Pleural effusion (water on the lungs)
Psychological trauma
Ammonia increased
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain

male:

Pain
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Disease progression
Fluid retention (an abnormal accumulation of fluid in the blood)
Headache (pain in head)
Polyarthritis (arthritis which involves 5 or more joints simultaneously)
White blood cell count decreased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood pressure increased

What are the common drug interactions of Imodium and Tradjenta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Fibromyalgia (a long-term condition which causes pain all over the body)
Mania (a state of abnormally elevated or irritable mood)
Neuropathy peripheral (surface nerve damage)
Renal failure (kidney dysfunction)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Chronic kidney disease

40-49:

Depression
Suicide attempt

50-59:

Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Vaginal haemorrhage (vaginal bleeding)
Anaemia (lack of blood)
Haematoma (collection of blood outside the blood vessels)
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Peripheral ischaemia (impaired circulation to an extremity)
Chronic kidney disease
Febrile neutropenia (fever with reduced white blood cells)
Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule)

60+:

Fluid retention (an abnormal accumulation of fluid in the blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Acute respiratory failure
Arrhythmia (irregular heartbeat)
Blood glucose increased
Burning sensation
Cardiac disorder
Cardiac failure
Chest pain
Colitis (inflammation of colon)

What are the existing conditions these people have? *

Pain: 16 people, 29.63%
High Blood Pressure: 13 people, 24.07%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 22.22%
Type 2 Diabetes: 11 people, 20.37%
Constipation: 7 people, 12.96%
Nausea (feeling of having an urge to vomit): 7 people, 12.96%
Multiple Myeloma (cancer of the plasma cells): 7 people, 12.96%
High Blood Cholesterol: 7 people, 12.96%
Stress And Anxiety: 6 people, 11.11%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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