Imodium and Trandate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Trandate (labetalol hydrochloride). Common drug interactions include abdominal infection among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Trandate. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Trandate?

Trandate has active ingredients of labetalol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 1,735 Trandate users. Check the latest studies of Trandate.

On Jul, 30, 2026

19 people who take Imodium and Trandate together, and have interactions are studied.

What are the common drug interactions of Imodium and Trandate, by gender? *:

female:

Abdominal infection
Enterocutaneous fistula
Hypoxia (low oxygen in tissues)
Leukocytosis (increased white blood cells)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Septic shock (shock due to blood infection)
Small intestinal obstruction (blockage in small intestine)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Renal tubular necrosis (death of kidney tubules)
Asthenia (weakness)

male:

Abdominal distension
Blood pressure systolic increased
Blood pressure diastolic decreased
Flatulence (flatus expelled through the anus)
Malignant neoplasm progression (cancer tumour came back)
Metastases to liver (cancer spreads to liver)
Pyrexia (fever)
Skin reaction
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Pulmonary oedema (fluid accumulation in the lungs)

What are the common drug interactions of Imodium and Trandate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abdominal distension
Asthenia (weakness)
Blood pressure systolic increased
Flatulence (flatus expelled through the anus)
Malignant neoplasm progression (cancer tumour came back)
Metastases to liver (cancer spreads to liver)
Pyrexia (fever)
Skin reaction
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Abdominal pain upper

60+:

Abdominal infection
Enterocutaneous fistula
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Dyspnoea (difficult or laboured respiration)
Hypoxia (low oxygen in tissues)
Leukocytosis (increased white blood cells)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Septic shock (shock due to blood infection)
Small intestinal obstruction (blockage in small intestine)
Encephalopathy (functioning of the brain is affected by some agent or condition)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 10 people, 52.63%
Pain: 6 people, 31.58%
Stress And Anxiety: 6 people, 31.58%
Depression: 5 people, 26.32%
Itching: 4 people, 21.05%
Constipation: 4 people, 21.05%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 4 people, 21.05%
Nausea And Vomiting: 4 people, 21.05%
Sedation: 4 people, 21.05%
Febrile Neutropenia (fever with reduced white blood cells): 4 people, 21.05%

* Approximation only. Some reports may have incomplete information.

Do you take Imodium and Trandate?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously