Imodium and Uloric drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Uloric (febuxostat). Common drug interactions include orthostatic hypotension among females and cough among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Uloric. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Uloric?

Uloric has active ingredients of febuxostat. It is often used in gout. eHealthMe is studying from 8,067 Uloric users. Check the latest studies of Uloric.

On Jul, 21, 2026

83 people who take Imodium and Uloric together, and have interactions are studied.

What are the common drug interactions of Imodium and Uloric, by gender? *:

female:

Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Renal cyst (kidney cyst)
Vitamin d deficiency
Balance disorder
Bladder disorder
Bone disorder
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Pain

male:

Cough
Rash
Pyrexia (fever)
Somnolence (a state of near-sleep, a strong desire for sleep)
Urinary tract infection
Arrhythmia supraventricular (irregular heartbeat supraventricular origin)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Dysphagia (a condition in which swallowing is difficult or painful)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Imodium and Uloric, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Death
Device related infection
Dizziness
Dyspnoea (difficult or laboured respiration)
Haematoma (collection of blood outside the blood vessels)
Local swelling (swelling at the site of some application of substance or injury)
Oesophageal adenocarcinoma metastatic (a cancer tumour of an epithelium in oesophagus spreads to other parts)
Pain
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Infusion site swelling
Joint injury
Kidney infection
Renal cyst (kidney cyst)
Sinusitis (inflammation of sinus)
Urinary tract infection
Bladder disorder
Asthma
Balance disorder

60+:

Chronic kidney disease
Pancreatitis (inflammation of pancreas)
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Muscle atrophy (a decrease in the mass of the muscle)
Nephrolithiasis (calculi in the kidneys)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Vitamin d deficiency
Cough
Pyrexia (fever)

What are the existing conditions these people have? *

High Blood Pressure: 14 people, 16.87%
Immunodeficiency Common Variable: 9 people, 10.84%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 10.84%
Multiple Myeloma (cancer of the plasma cells): 8 people, 9.64%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 8 people, 9.64%
Primary Myelofibrosis (primary disorder of the bone marrow): 7 people, 8.43%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 8.43%
Pain: 6 people, 7.23%
Stress And Anxiety: 5 people, 6.02%
High Blood Cholesterol: 5 people, 6.02%

* Approximation only. Some reports may have incomplete information.

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