Imodium and Xopenex hfa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Xopenex hfa (levalbuterol tartrate). Common drug interactions include drug ineffective among females and infective pulmonary exacerbation of cystic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Xopenex hfa. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Xopenex hfa?

Xopenex hfa has active ingredients of levalbuterol tartrate. It is often used in asthma. eHealthMe is studying from 2,529 Xopenex hfa users. Check the latest studies of Xopenex hfa.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

19 people who take Imodium and Xopenex hfa together, and have interactions are studied.

Imodium and Xopenex hfa drug interactions.

What are the common drug interactions of Imodium and Xopenex Hfa, by gender? *:

female:

Drug ineffective
Dysphonia (speech disorder attributable to a disorder of phonation)
Injection site pain
Pulmonary oedema (fluid accumulation in the lungs)
Weight decreased
Oedema peripheral (superficial swelling)
Pain in extremity
Pneumonia
Staphylococcal infection (an infection with staphylococcus bacteria)
Blood pressure fluctuation

male:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Nausea (feeling of having an urge to vomit)
Vomiting
Injection site pain
Pain
Pain of skin
Sleep disorder

What are the common drug interactions of Imodium and Xopenex Hfa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Nausea (feeling of having an urge to vomit)
Vomiting

30-39:

n/a

40-49:

n/a

50-59:

Injection site erythema (redness at injection site)
Injection site pruritus (severe itching at injection site)
Injection site rash
Nausea (feeling of having an urge to vomit)
Vomiting

60+:

Oedema peripheral (superficial swelling)
Pain in extremity
Abdominal pain
Abdominal wall haematoma (abdominal wall blood clotting)
Anaemia (lack of blood)
Anaemia of chronic disease
Aspartate aminotransferase increased
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain

What are the existing conditions these people have? *

Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 5 people, 26.32%
Restless Leg Syndrome (a powerful urge to move your legs): 5 people, 26.32%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 15.79%
Irritable Bowel Syndrome: 3 people, 15.79%
Drowsiness: 3 people, 15.79%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 15.79%
Nausea (feeling of having an urge to vomit): 2 people, 10.53%
Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 2 people, 10.53%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 10.53%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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