Imodium and Zebeta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Zebeta (bisoprolol fumarate). Common drug interactions include blood sodium decreased among females and back disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Zebeta. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Zebeta?

Zebeta has active ingredients of bisoprolol fumarate. It is often used in high blood pressure. eHealthMe is studying from 1,734 Zebeta users. Check the latest studies of Zebeta.



On Jul, 07, 2026

12 people who take Imodium and Zebeta together, and have interactions are studied.

Imodium and Zebeta drug interactions.

What are the common drug interactions of Imodium and Zebeta, by gender? *:

female:

  1. Blood sodium decreased
  2. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Dehydration (dryness resulting from the removal of water)
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Hypotension (abnormally low blood pressure)
  7. Oral candidiasis (fungal infection of mouth)
  8. Ovarian cyst (fluid filled sac of the ovary)
  9. Pain
  10. Pain of skin

male:

  1. Back disorder
  2. Balance disorder
  3. Fall
  4. Mobility decreased (ability to move is reduced)
  5. Peripheral neuropathy (damage to nerves of the peripheral nervous system)
  6. Pneumonia
  7. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

What are the common drug interactions of Imodium and Zebeta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Blood sodium decreased
  4. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Dehydration (dryness resulting from the removal of water)
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Hypotension (abnormally low blood pressure)
  9. Oral candidiasis (fungal infection of mouth)
  10. Ovarian cyst (fluid filled sac of the ovary)

40-49:

  1. Hyperuricaemia (level of uric acid in the blood that is abnormally high)

50-59:

  1. Death

60+:

  1. Alopecia (absence of hair from areas of the body)
  2. Aphasia (damage to the parts of the brain that control language)
  3. Pain in extremity
  4. Peripheral neuropathy (damage to nerves of the peripheral nervous system)
  5. Skin disorder (skin disease)
  6. Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
  7. Tremor (trembling or shaking movements in one or more parts of your body)
  8. Back pain
  9. Fall
  10. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Pain: 3 people, 25.00%
  2. Nausea (feeling of having an urge to vomit): 3 people, 25.00%
  3. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 25.00%
  4. Arrhythmias (irregular heartbeat): 2 people, 16.67%
  5. Stress And Anxiety: 2 people, 16.67%
  6. Depression: 2 people, 16.67%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
  8. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 8.33%
  9. Breast Cancer: 1 person, 8.33%
  10. Breast Cancer Female: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Imodium and Zebeta?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Imodium and Zebeta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zebeta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zebeta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride and bisoprolol fumarate (the active ingredients of Imodium and Zebeta, respectively), and Imodium and Zebeta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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