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Indapamide and Esbriet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Indapamide (indapamide) and Esbriet (pirfenidone). Common drug interactions include abdominal pain upper among females and influenza among males.

The phase IV clinical study analyzes what interactions people have when they take Indapamide and Esbriet. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Indapamide?

Indapamide has active ingredients of indapamide. It is often used in high blood pressure. eHealthMe is studying from 22,152 Indapamide users. Check the latest studies of Indapamide.

What is Esbriet?

Esbriet has active ingredients of pirfenidone. eHealthMe is studying from 39,858 Esbriet users. Check the latest studies of Esbriet.

On Jul, 27, 2026

33 people who take Indapamide and Esbriet together, and have interactions are studied.

Indapamide and Esbriet drug interactions.

What are the common drug interactions of Indapamide and Esbriet, by gender? *:

female:

  1. Abdominal pain upper
  2. Back injury
  3. Pain
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Spinal fracture (fracture in one of vertebrae)
  6. Abdominal discomfort
  7. Weight decreased
  8. Nausea (feeling of having an urge to vomit)
  9. Asthenia (weakness)
  10. Diarrhoea

male:

  1. Influenza
  2. Cough
  3. Flatulence (flatus expelled through the anus)
  4. Lacrimation increased
  5. Vision blurred
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Urinary tract infection
  8. Herpes zoster
  9. Acute myocardial infarction (acute heart attack)
  10. Death

What are the common drug interactions of Indapamide and Esbriet, by age (0-1 to 60+)? *:

0-1:

  1. Herpes zoster

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Influenza

50-59:

n/a

60+:

  1. Abdominal pain upper
  2. Back injury
  3. Decreased appetite
  4. Dizziness
  5. Dyspnoea (difficult or laboured respiration)
  6. Fatigue (feeling of tiredness)
  7. Flatulence (flatus expelled through the anus)
  8. Headache (pain in head)
  9. Lacrimation increased
  10. Vision blurred

What are the existing conditions these people have? *

  1. Idiopathic Pulmonary Fibrosis (chronic lung disease): 22 people, 66.67%
  2. Interstitial Lung Disease: 6 people, 18.18%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 12.12%

* Approximation only. Some reports may have incomplete information.

Do you take Indapamide and Esbriet?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Indapamide and Esbriet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Indapamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Esbriet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Indapamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Esbriet and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on indapamide and pirfenidone (the active ingredients of Indapamide and Esbriet, respectively), and Indapamide and Esbriet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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