Indapamide and Lomotil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Indapamide (indapamide) and Lomotil (atropine sulfate; diphenoxylate hydrochloride). Common drug interactions include hyperhidrosis among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Indapamide and Lomotil. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Indapamide?

Indapamide has active ingredients of indapamide. It is often used in high blood pressure. eHealthMe is studying from 22,152 Indapamide users. Check the latest studies of Indapamide.

What is Lomotil?

Lomotil has active ingredients of atropine sulfate; diphenoxylate hydrochloride. It is often used in diarrhea. eHealthMe is studying from 19,184 Lomotil users. Check the latest studies of Lomotil.



On Jul, 21, 2026

27 people who take Indapamide and Lomotil together, and have interactions are studied.

Indapamide and Lomotil drug interactions.

What are the common drug interactions of Indapamide and Lomotil, by gender? *:

female:

  1. Hyperhidrosis (abnormally increased sweating)
  2. Adverse event
  3. Allergy to chemicals
  4. Alopecia (absence of hair from areas of the body)
  5. Arthralgia (joint pain)
  6. Asthenia (weakness)
  7. Colon cancer
  8. Disability
  9. Dry skin
  10. Dysphonia (speech disorder attributable to a disorder of phonation)

male:

  1. Fatigue (feeling of tiredness)
  2. Muscular weakness (muscle weakness)
  3. Renal impairment (severely reduced kidney function)
  4. Anxiety
  5. Arthralgia (joint pain)
  6. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  7. Bone pain
  8. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  9. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  10. Disease progression

What are the common drug interactions of Indapamide and Lomotil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Blood testosterone decreased

60+:

  1. Fatigue (feeling of tiredness)
  2. Muscular weakness (muscle weakness)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal failure (kidney dysfunction)
  5. Renal impairment (severely reduced kidney function)
  6. Anxiety
  7. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  8. Bone pain
  9. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  10. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 18.52%
  2. Neuralgia (pain in one or more nerves): 4 people, 14.81%
  3. Multiple Myeloma (cancer of the plasma cells): 3 people, 11.11%
  4. Breast Cancer: 3 people, 11.11%
  5. Renal Cell Carcinoma (a kidney cancer): 2 people, 7.41%
  6. Pain: 2 people, 7.41%
  7. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 7.41%
  8. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 2 people, 7.41%
  9. Joint Pain: 2 people, 7.41%
  10. Headache (pain in head): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Indapamide and Lomotil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Indapamide and Lomotil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Indapamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lomotil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Indapamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lomotil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on indapamide and atropine sulfate; diphenoxylate hydrochloride (the active ingredients of Indapamide and Lomotil, respectively), and Indapamide and Lomotil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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