Inlyta and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Inlyta (axitinib) and Compazine (prochlorperazine maleate). Common drug interactions include drug ineffective among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Inlyta and Compazine. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Inlyta?

Inlyta has active ingredients of axitinib. eHealthMe is studying from 17,662 Inlyta users. Check the latest studies of Inlyta.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in nausea and vomiting. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.



On Aug, 02, 2026

49 people who take Inlyta and Compazine together, and have interactions are studied.

Inlyta and Compazine drug interactions.

What are the common drug interactions of Inlyta and Compazine, by gender? *:

female:

  1. Drug ineffective
  2. Epistaxis (bleed from the nose)
  3. Hand-foot-and-mouth disease
  4. Hot flush (sudden feelings of heat)
  5. Hypersensitivity
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Muscle spasms (muscle contraction)
  8. Pneumonia
  9. Pruritus (severe itching of the skin)
  10. Stomatitis (inflammation of mucous membrane of mouth)

male:

  1. Diarrhoea
  2. Decreased appetite
  3. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  4. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  5. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  6. Stupor (lack of critical cognitive function and level of consciousness)
  7. Dysphonia (speech disorder attributable to a disorder of phonation)
  8. Blood pressure increased
  9. Headache (pain in head)
  10. Asthenia (weakness)

What are the common drug interactions of Inlyta and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Death
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Drug ineffective
  4. Neoplasm progression (growth of tumour)

40-49:

n/a

50-59:

  1. Hemiplegia (paralysis of one side of the body)
  2. Malignant neoplasm progression (cancer tumour came back)
  3. Osteonecrosis (death of bone)
  4. Skin disorder (skin disease)
  5. Skin exfoliation (removal of the oldest dead skin cells)
  6. Urinary bladder haemorrhage (urinary bladder bleeding)
  7. Blood pressure increased
  8. Cholecystitis (infection of gallbladder)
  9. Dysphonia (speech disorder attributable to a disorder of phonation)
  10. Enteritis (inflammation of the small intestine)

60+:

  1. Diarrhoea
  2. Decreased appetite
  3. Hypertension (high blood pressure)
  4. Pain
  5. Skin exfoliation (removal of the oldest dead skin cells)
  6. Renal cell carcinoma (a kidney cancer)
  7. Abdominal pain
  8. Asthenia (weakness)
  9. Back pain
  10. Burning sensation

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 33 people, 67.35%
  2. Nausea (feeling of having an urge to vomit): 17 people, 34.69%
  3. Pain: 9 people, 18.37%
  4. High Blood Pressure: 7 people, 14.29%
  5. Diarrhea: 4 people, 8.16%
  6. Diabetes: 4 people, 8.16%
  7. Constipation: 4 people, 8.16%
  8. Stress And Anxiety: 3 people, 6.12%
  9. Oral Pain: 3 people, 6.12%
  10. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

Do you take Inlyta and Compazine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Inlyta and Compazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Inlyta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Compazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Inlyta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Compazine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on axitinib and prochlorperazine maleate (the active ingredients of Inlyta and Compazine, respectively), and Inlyta and Compazine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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