Innohep and Lonsurf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Innohep (tinzaparin sodium) and Lonsurf (tipiracil hydrochloride; trifluridine). Common drug interactions include pleural effusion among females and diarrhoea haemorrhagic among males.

The phase IV clinical study analyzes what interactions people have when they take Innohep and Lonsurf. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Innohep?

Innohep has active ingredients of tinzaparin sodium. eHealthMe is studying from 9,243 Innohep users. Check the latest studies of Innohep.

What is Lonsurf?

Lonsurf has active ingredients of tipiracil hydrochloride; trifluridine. eHealthMe is studying from 10,077 Lonsurf users. Check the latest studies of Lonsurf.



On Jul, 06, 2026

11 people who take Innohep and Lonsurf together, and have interactions are studied.

Innohep and Lonsurf drug interactions.

What are the common drug interactions of Innohep and Lonsurf, by gender? *:

female:

  1. Pleural effusion (water on the lungs)
  2. Device related infection
  3. Ascites (accumulation of fluid in the abdominal cavity)
  4. Disease progression
  5. Drug intolerance (drug sensitivity)
  6. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  7. Pneumonia
  8. Rash
  9. Septic shock (shock due to blood infection)
  10. Malignant neoplasm progression (cancer tumour came back)

male:

  1. Diarrhoea haemorrhagic (bloody diarrhoea)
  2. Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
  3. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  4. General symptom
  5. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  6. Pain
  7. Subileus

What are the common drug interactions of Innohep and Lonsurf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Oedema peripheral (superficial swelling)
  3. Pleural effusion (water on the lungs)
  4. Device related infection
  5. Ascites (accumulation of fluid in the abdominal cavity)
  6. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  7. Rash
  8. Jugular vein thrombosis (clot in jugular vein)

50-59:

  1. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

60+:

  1. Diarrhoea haemorrhagic (bloody diarrhoea)
  2. Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Disease progression
  5. Drug intolerance (drug sensitivity)
  6. Pneumonia
  7. Septic shock (shock due to blood infection)
  8. Subileus

What are the existing conditions these people have? *

  1. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 7 people, 63.64%
  2. High Blood Pressure: 5 people, 45.45%
  3. Nausea (feeling of having an urge to vomit): 5 people, 45.45%
  4. Stress And Anxiety: 5 people, 45.45%
  5. Bleeding Disorders: 4 people, 36.36%
  6. Gastrointestinal Infection (infection of stomach and intestine): 3 people, 27.27%
  7. Pain: 3 people, 27.27%
  8. Hypokalemia (low potassium): 3 people, 27.27%
  9. Colon Cancer Metastatic (cancer of colon spreads to other part of body): 2 people, 18.18%
  10. Abdominal Pain: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Innohep and Lonsurf?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Innohep and Lonsurf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Innohep:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lonsurf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Innohep and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lonsurf and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tinzaparin sodium and tipiracil hydrochloride; trifluridine (the active ingredients of Innohep and Lonsurf, respectively), and Innohep and Lonsurf (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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