Inositol and B12 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Inositol (inositol) and B12 (cobalamin). Common drug interactions include suicidal ideation among females and memory impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Inositol and B12. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.

What is Inositol?

Inositol has active ingredients of inositol. It is often used in stress and anxiety. eHealthMe is studying from 828 Inositol users. Check the latest studies of Inositol.

What is B12?

B12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 121,894 B12 users. Check the latest studies of B12.



On Aug, 11, 2026

95 people who take Inositol and B12 together, and have interactions are studied.

Inositol and B12 drug interactions.

What are the common drug interactions of Inositol and B12, by gender? *:

female:

  1. Suicidal ideation
  2. Surgery
  3. Tremor (trembling or shaking movements in one or more parts of your body)
  4. Visual impairment
  5. Weight decreased
  6. White blood cell count decreased
  7. Injection site mass
  8. Injection site pain
  9. Mouth ulceration (mouth ulcers)
  10. Abasia (inability to walk)

male:

  1. Memory impairment
  2. Pain
  3. Gait spastic
  4. Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Insomnia (sleeplessness)
  7. Micturition urgency (urgency to pass the urine)
  8. Monoparesis (one limb is very weak, but not completely paralyzed)
  9. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  10. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

What are the common drug interactions of Inositol and B12, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  2. Drug ineffective
  3. Dyskinesia (abnormality or impairment of voluntary movement)
  4. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  5. Gaze palsy (disorders affecting the ability to move both eyes in the same direction)
  6. Lip discolouration
  7. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

20-29:

  1. Blindness
  2. Gait disturbance
  3. Lymphocyte count decreased
  4. Menstruation delayed (late menstruation cycle)
  5. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  6. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  7. Platelet count decreased
  8. Visual impairment
  9. Weight decreased
  10. White blood cell count decreased

30-39:

  1. Disease recurrence
  2. Drug ineffective
  3. Dry skin
  4. Muscle spasms (muscle contraction)
  5. Post procedural infection
  6. Surgery
  7. Tooth extraction

40-49:

  1. Ataxia (loss of full control of bodily movements)
  2. Balance disorder
  3. Bradycardia (abnormally slow heart action)
  4. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  5. Dizziness
  6. Dysarthria (speech disorder)
  7. Erectile dysfunction
  8. Fall
  9. Gait disturbance
  10. Gait spastic

50-59:

  1. Deafness
  2. Depressed mood
  3. Diarrhoea
  4. Drug dependence
  5. Drug ineffective
  6. Dry mouth
  7. Dysgeusia (disorder of the sense of taste)
  8. Erythema (redness of the skin)
  9. Eye pruritus (eye itching)
  10. Feeling hot

60+:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Loss of consciousness
  4. Memory impairment
  5. Oropharyngeal pain
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  7. Tendon rupture (tear of tendon)
  8. Throat irritation
  9. Tooth disorder (tooth disease)
  10. Tooth infection

What are the existing conditions these people have? *

  1. Pain: 27 people, 28.42%
  2. Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 11 people, 11.58%
  3. Parkinson's Disease: 7 people, 7.37%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 6.32%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Inositol and B12?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Inositol and B12:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Inositol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of B12:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Inositol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between B12 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on inositol and cobalamin (the active ingredients of Inositol and B12, respectively), and Inositol and B12 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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