Insulin and Fentanyl citrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Insulin (insulin pork) and Fentanyl citrate (fentanyl citrate). Common drug interactions include respiratory failure among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Insulin and Fentanyl citrate. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Insulin?

Insulin has active ingredients of insulin pork. It is often used in diabetes. eHealthMe is studying from 50,203 Insulin users. Check the latest studies of Insulin.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.

On Jul, 28, 2026

73 people who take Insulin and Fentanyl citrate together, and have interactions are studied.

Insulin and Fentanyl citrate drug interactions.

What are the common drug interactions of Insulin and Fentanyl Citrate, by gender? *:

female:

Respiratory failure (inadequate gas exchange by the respiratory system)
Pleural effusion (water on the lungs)
Cardiac failure congestive
Depression
Death
Haematoma (collection of blood outside the blood vessels)
Hypotension (abnormally low blood pressure)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Pulmonary oedema (fluid accumulation in the lungs)

male:

Dyspnoea (difficult or laboured respiration)
Low density lipoprotein increased (cholesterol increased in blood)
Blood urea increased
Fatigue (feeling of tiredness)
Anal abscess
Anal fissure
Chills (felling of cold)
Haematochezia (passage of stools containing blood)
Lung infection
Platelet count decreased

What are the common drug interactions of Insulin and Fentanyl Citrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cardiogenic shock (inadequate circulation of blood)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Dizziness
Drug ineffective
Drug intolerance (drug sensitivity)
Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
Gastrointestinal necrosis (destruction of gastrointestinal organ)
Genital pain (pain in genital)
Hepatic failure (liver failure)
Hepatic necrosis (large portions of liver die off due to severe liver disease)

20-29:

Cardiac arrest
Cardiomyopathy (weakening of the heart muscle)
Diabetes insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function)
Haemodynamic instability (disturbances in the blood movement in our body)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Hyperthermia (body temperature greatly above normal)
Hypotension (abnormally low blood pressure)
Maternal exposure during pregnancy (use of substance during pregnancy)
Normal newborn
Pneumonia

30-39:

Anal abscess
Anal fissure
Blood creatinine increased
Blood urea increased
Chills (felling of cold)
Cough
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Haematochezia (passage of stools containing blood)

40-49:

Haemoglobin decreased
Platelet count decreased
Bilirubin conjugated increased
Blood albumin decreased
Blood glucose increased
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Low density lipoprotein increased (cholesterol increased in blood)
Lymphocyte count decreased
Protein urine present
Red blood cells urine positive

50-59:

Fungal infection
Hypertension (high blood pressure)
Leukopenia (less number of white blood cells in blood)
Liver injury
Palpitations (feelings or sensations that your heart is pounding or racing)
Pyrexia (fever)
Urinary tract infection
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
Fall

60+:

Pneumonia
Thrombocytopenia (decrease of platelets in blood)
Oedema peripheral (superficial swelling)
Orthopnoea (shortness of breath (dyspnea) when lying down)
Rash vesicular (rash with a small bubble)
Renal failure acute (rapid kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Cardiac failure congestive
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Death

What are the existing conditions these people have? *

Constipation: 22 people, 30.14%
High Blood Pressure: 22 people, 30.14%
Urination - Excessive Volume: 18 people, 24.66%
Anaesthesia: 14 people, 19.18%
Blood Glucose Increased: 13 people, 17.81%
Sedation: 10 people, 13.70%
Nausea And Vomiting: 9 people, 12.33%
Fever: 8 people, 10.96%
Hypotension (abnormally low blood pressure): 7 people, 9.59%
Anaemia (lack of blood): 7 people, 9.59%

* Approximation only. Some reports may have incomplete information.

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