Intron a and Demerol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Intron a (interferon alfa-2b) and Demerol (meperidine hydrochloride). Common drug interactions include nausea among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Intron a and Demerol. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Intron a?

Intron a has active ingredients of interferon alfa-2b. eHealthMe is studying from 9,320 Intron a users. Check the latest studies of Intron a.

What is Demerol?

Demerol has active ingredients of meperidine hydrochloride. It is often used in pain. eHealthMe is studying from 12,706 Demerol users. Check the latest studies of Demerol.



On Jul, 15, 2026

18 people who take Intron a and Demerol together, and have interactions are studied.

Intron a and Demerol drug interactions.

What are the common drug interactions of Intron A and Demerol, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Dehydration (dryness resulting from the removal of water)
  3. Suicidal ideation
  4. Blood creatinine increased
  5. Blood urea increased
  6. Decreased appetite
  7. Infection
  8. Injection site reaction
  9. Insomnia (sleeplessness)
  10. Necrosis ischaemic (death of cell due to lack of blood supply)

male:

  1. Headache (pain in head)
  2. Pyrexia (fever)
  3. Herpes simplex (herpes simplex is a common viral infection)
  4. Hyperglycaemia (high blood sugar)
  5. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  6. Hypokalaemia (low potassium)
  7. Hypotension (abnormally low blood pressure)
  8. Klebsiella infection
  9. Necrosis (the death of body tissue)
  10. Oxygen saturation decreased

What are the common drug interactions of Intron A and Demerol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Gait abnormal
  2. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  3. Restlessness (not able to rest)
  4. Tardive dyskinesia (a disorder that involves involuntary movements)

30-39:

  1. Abdominal distension
  2. Agitation (state of anxiety or nervous excitement)
  3. Back pain
  4. Crying
  5. Dehydration (dryness resulting from the removal of water)
  6. Depression
  7. Diarrhoea
  8. Headache (pain in head)
  9. Influenza like illness
  10. Insomnia (sleeplessness)

40-49:

  1. Blood urea increased
  2. Cellulitis (infection under the skin)
  3. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  4. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  5. Decreased appetite
  6. Dehydration (dryness resulting from the removal of water)
  7. Depressed level of consciousness
  8. Herpes simplex (herpes simplex is a common viral infection)
  9. Hyperglycaemia (high blood sugar)
  10. Hypocalcaemia (levels of calcium in blood serum are abnormally low)

50-59:

  1. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  2. Ventricular fibrillation (abnormally irregular heart rhythm)

60+:

n/a

What are the existing conditions these people have? *

  1. Hepatitis C: 3 people, 16.67%
  2. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 1 person, 5.56%
  3. Malignant Melanoma (skin cancer rises from melancytes): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Intron a and Demerol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Intron a and Demerol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Intron a:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Demerol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Intron a and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Demerol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on interferon alfa-2b and meperidine hydrochloride (the active ingredients of Intron a and Demerol, respectively), and Intron a and Demerol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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