Intron a and Rocephin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Intron a (interferon alfa-2b) and Rocephin (ceftriaxone sodium). Common drug interactions include weight decreased among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Intron a and Rocephin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Intron a?
Intron a has active ingredients of interferon alfa-2b. eHealthMe is studying from 9,320 Intron a users. Check the latest studies of Intron a.
What is Rocephin?
Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
16 people who take Intron a and Rocephin together, and have interactions are studied.

What are the common drug interactions of Intron A and Rocephin, by gender? *:
female:
- Weight decreased
- Oedema peripheral (superficial swelling)
- Drug toxicity
- General physical health deterioration (weak health status)
- Drug resistance (reduction in effectiveness of a drug)
- Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)
- Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
- Blood lactate dehydrogenase increased
- Pleural effusion (water on the lungs)
- Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
male:
- Anxiety
- Aphasia (damage to the parts of the brain that control language)
- Aortic arteriosclerosis (hardening of the aortic arteries)
- Back pain
- Bone disorder
- Bowel movement irregularity
- Cellulitis (infection under the skin)
- Cerebral atrophy (decrement in size of brain)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
What are the common drug interactions of Intron A and Rocephin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Pleural effusion (water on the lungs)
40-49:
n/a
50-59:
n/a
60+:
- Weight decreased
- Renal failure acute (rapid kidney dysfunction)
- Abdominal discomfort
- Abdominal pain
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anaemia (lack of blood)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Aortic arteriosclerosis (hardening of the aortic arteries)
- Back pain
- Bone disorder
What are the existing conditions these people have? *
- Urinary Tract Infection: 7 people, 43.75%
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 6.25%
- Oedema Peripheral (superficial swelling): 1 person, 6.25%
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Intron a and Rocephin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Intron a and Rocephin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Intron a:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Rocephin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Intron a and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rocephin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on interferon alfa-2b and ceftriaxone sodium (the active ingredients of Intron a and Rocephin, respectively), and Intron a and Rocephin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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