Invokana and Flovent drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Invokana (canagliflozin) and Flovent (fluticasone propionate). Common drug interactions include pain among females and benign prostatic hyperplasia among males.

The phase IV clinical study analyzes what interactions people have when they take Invokana and Flovent. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Invokana?

Invokana has active ingredients of canagliflozin. It is often used in diabetes. eHealthMe is studying from 29,937 Invokana users. Check the latest studies of Invokana.

What is Flovent?

Flovent has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 44,817 Flovent users. Check the latest studies of Flovent.



On Jul, 17, 2026

46 people who take Invokana and Flovent together, and have interactions are studied.

Invokana and Flovent drug interactions.

What are the common drug interactions of Invokana and Flovent, by gender? *:

female:

  1. Pain
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Peripheral swelling
  4. Dehydration (dryness resulting from the removal of water)
  5. Urinary tract infection
  6. Vulvovaginal mycotic infection (vulvovaginal fungal infection)
  7. Burning sensation
  8. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  9. Gait disturbance
  10. Nephrolithiasis (calculi in the kidneys)

male:

  1. Benign prostatic hyperplasia (benign enlargement of the prostate)
  2. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  3. Nephrolithiasis (calculi in the kidneys)
  4. Oral candidiasis (fungal infection of mouth)
  5. Presyncope
  6. Pyrexia (fever)
  7. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  8. Sinusitis (inflammation of sinus)
  9. Urinary tract infection
  10. Hypersensitivity

What are the common drug interactions of Invokana and Flovent, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Renal cell carcinoma (a kidney cancer)
  2. Back pain
  3. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  4. Haematemesis (vomiting of blood)
  5. Hyperphagia (an abnormal appetite for food)
  6. Hypersensitivity
  7. Hysterectomy
  8. Nausea (feeling of having an urge to vomit)
  9. Oral candidiasis (fungal infection of mouth)
  10. Pain in extremity

50-59:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Pain
  3. Burning sensation
  4. Gait disturbance
  5. Constipation
  6. Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
  7. Drug ineffective
  8. Eye swelling
  9. Fatigue (feeling of tiredness)
  10. Urine output increased

60+:

  1. Dehydration (dryness resulting from the removal of water)
  2. Urinary tract infection
  3. Bladder disorder
  4. Cardiovascular disorder (heart diseases)
  5. Chest discomfort
  6. Chronic kidney disease
  7. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  8. Dry mouth
  9. Dystonia (abnormal muscle tone)
  10. Dysuria (painful or difficult urination)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 30.43%
  2. Type 2 Diabetes: 10 people, 21.74%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 13.04%
  4. Osteoporosis (bones weak and more likely to break): 5 people, 10.87%
  5. Neuropathy Peripheral (surface nerve damage): 5 people, 10.87%
  6. High Blood Pressure: 5 people, 10.87%
  7. Skin Blushing/flushing (a sudden reddening of the face, neck): 3 people, 6.52%
  8. High Blood Cholesterol: 3 people, 6.52%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.52%
  10. Depression: 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Invokana and Flovent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Invokana:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Flovent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Invokana and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flovent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on canagliflozin and fluticasone propionate (the active ingredients of Invokana and Flovent, respectively), and Invokana and Flovent (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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