Isentress and Vimpat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isentress (raltegravir potassium) and Vimpat (lacosamide). Common drug interactions include atrioventricular block among females and drug level increased among males.

The phase IV clinical study analyzes what interactions people have when they take Isentress and Vimpat. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Isentress?

Isentress has active ingredients of raltegravir potassium. It is often used in hiv infection. eHealthMe is studying from 16,529 Isentress users. Check the latest studies of Isentress.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,832 Vimpat users. Check the latest studies of Vimpat.

On Aug, 09, 2026

25 people who take Isentress and Vimpat together, and have interactions are studied.

What are the common drug interactions of Isentress and Vimpat, by gender? *:

female:

Atrioventricular block (heart block)
Cardiac arrest
Hyperkalaemia (damage to or disease of the kidney)
Acute respiratory distress syndrome
Abortion induced (medically referred abortion)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress

male:

Drug level increased
Encephalitis cytomegalovirus (inflammation of the brain due to cytomegalovirus)
Bone density decreased
Death
Emotional distress
Foot fracture
Osteoporosis (bones weak and more likely to break)
Pain
Calculus urinary (stone in urinary system)
Chronic kidney disease

What are the common drug interactions of Isentress and Vimpat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Atrioventricular block (heart block)
Cardiac arrest
Hyperkalaemia (damage to or disease of the kidney)
Acute respiratory distress syndrome
Abortion induced (medically referred abortion)
Immune reconstitution syndrome (immune recovery syndrome)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

30-39:

n/a

40-49:

Drug level increased
Encephalitis cytomegalovirus (inflammation of the brain due to cytomegalovirus)
Liver disorder (liver diseases)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Oral herpes (viral infection of mouth)
Weight increased
Malaise (a feeling of general discomfort or uneasiness)
Calculus urinary (stone in urinary system)
Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

50-59:

Palpitations (feelings or sensations that your heart is pounding or racing)
Anaemia (lack of blood)
Sleep disorder
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Death
Emotional distress
Gait disturbance
Pain

60+:

n/a

What are the existing conditions these people have? *

Central Nervous System Lymphoma (cancer of central nervous system forms in lymph tissue): 9 people, 36.00%
High Blood Pressure: 5 people, 20.00%
Neuropathy Peripheral (surface nerve damage): 4 people, 16.00%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 3 people, 12.00%
Sedation: 3 people, 12.00%
Hypokalemia (low potassium): 3 people, 12.00%
Blood Phosphorus Decreased: 3 people, 12.00%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 8.00%
Rickets (softening of bones): 2 people, 8.00%
Pain: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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