Isoflurane and Sufentanil citrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isoflurane (isoflurane) and Sufentanil citrate (sufentanil citrate). Common drug interactions include hypertension among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Isoflurane and Sufentanil citrate. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Isoflurane?

Isoflurane has active ingredients of isoflurane. eHealthMe is studying from 2,917 Isoflurane users. Check the latest studies of Isoflurane.

What is Sufentanil citrate?

Sufentanil citrate has active ingredients of sufentanil citrate. eHealthMe is studying from 1,794 Sufentanil citrate users. Check the latest studies of Sufentanil citrate.

On Jul, 26, 2026

55 people who take Isoflurane and Sufentanil citrate together, and have interactions are studied.

Isoflurane and Sufentanil citrate drug interactions.

What are the common drug interactions of Isoflurane and Sufentanil Citrate, by gender? *:

female:

Hypertension (high blood pressure)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Acute circulatory failure (shock)
Atrial thrombosis (blood clot that develops in an artery)
Blood lactate dehydrogenase increased
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Emotional distress
Face oedema (swelling of face)

male:

Hypotension (abnormally low blood pressure)
Renal failure (kidney dysfunction)
Venous thrombosis (blood clot (thrombus) that forms within a vein)
Hyperthermia malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions)
Alanine aminotransferase increased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Cardiac procedure complication
Catheter site haemorrhage (bleeding at catheter site)
Depression

What are the common drug interactions of Isoflurane and Sufentanil Citrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Acute generalised exanthematous pustulosis (acute febrile drug eruption)
Heart rate increased
Hyperthermia malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions)
Muscle rigidity (muscle stiffness)
Pco2 increased
Pyrexia (fever)
Rash

20-29:

n/a

30-39:

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Alanine aminotransferase increased
Anaesthetic complication cardiac
Aspartate aminotransferase increased
Blood bicarbonate decreased
Blood chloride increased
Blood glucose increased
Blood lactic acid increased
Blood ph decreased
Blood potassium decreased

40-49:

Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Hypotension (abnormally low blood pressure)
Polyuria (production of too much dilute urine)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Hypertension (high blood pressure)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
Electrocardiogram qt prolonged
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Arrhythmia (irregular heartbeat)

50-59:

Oxygen saturation decreased
Pain
Renal failure acute (rapid kidney dysfunction)
Renal injury (kidney injury)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Acute respiratory failure
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Apnoea (suspension of external breathing)
Atrioventricular dissociation (av block)

60+:

Disseminated intravascular coagulation (systemic activation of blood coagulation)
Hypotension (abnormally low blood pressure)
Injury
Pain
Pulmonary artery thrombosis (blockage of the main artery of the lung)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Renal failure (kidney dysfunction)
Thrombosis (formation of a blood clot inside a blood vessel)
Venous thrombosis (blood clot (thrombus) that forms within a vein)
Alanine aminotransferase increased

What are the existing conditions these people have? *

Anaesthesia: 12 people, 21.82%
High Blood Pressure: 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

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