Isoptin and Cyclophosphamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isoptin (verapamil hydrochloride) and Cyclophosphamide (cyclophosphamide). Common drug interactions include anaemia among females and haemorrhagic stroke among males.

The phase IV clinical study analyzes what interactions people have when they take Isoptin and Cyclophosphamide. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Isoptin?

Isoptin has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,539 Isoptin users. Check the latest studies of Isoptin.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.

On Jul, 29, 2026

30 people who take Isoptin and Cyclophosphamide together, and have interactions are studied.

Isoptin and Cyclophosphamide drug interactions.

What are the common drug interactions of Isoptin and Cyclophosphamide, by gender? *:

female:

Anaemia (lack of blood)
Bone marrow failure
Metastases to central nervous system (cancer spreads to central nervous system)
Metastases to lymph nodes (cancer spreads to lymph node)
Metastases to retroperitoneum (cancer spreads to retroperitonium)
Neutropenia (an abnormally low number of neutrophils)
Thrombocytopenia (decrease of platelets in blood)
Pyrexia (fever)
Dehydration (dryness resulting from the removal of water)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

male:

Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Thrombocytopenia (decrease of platelets in blood)
Confusional state
Groin pain
B-cell lymphoma (blood cancer affecting b cells)
Drug resistance (reduction in effectiveness of a drug)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Sepsis (a severe blood infection that can lead to organ failure and death)
Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do)
Disease progression

What are the common drug interactions of Isoptin and Cyclophosphamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Capillary leak syndrome (capillary leaks plasma)
Encephalitis (inflammation of the brain)

50-59:

Thrombocytopenia (decrease of platelets in blood)
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Escherichia infection (bacterial infection by escherichia coli)
Rectal haemorrhage (bleeding from anus)
Septic shock (shock due to blood infection)
Anaemia (lack of blood)
Bone marrow failure
Metastases to central nervous system (cancer spreads to central nervous system)
Metastases to lymph nodes (cancer spreads to lymph node)
Metastases to retroperitoneum (cancer spreads to retroperitonium)

60+:

Pyrexia (fever)
Dehydration (dryness resulting from the removal of water)
Leukopenia (less number of white blood cells in blood)
Loss of consciousness
Neutropenia (an abnormally low number of neutrophils)
Pleuropericarditis (inflammation of the pleura and pericardium)
Urinary tract infection
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Hypotension (abnormally low blood pressure)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the existing conditions these people have? *

Peripheral T-Cell Lymphoma Unspecified (peripheral t-cell cancer unspecified): 5 people, 16.67%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 16.67%
Burkitt Lymphoma (cancer of the lymphatic system): 5 people, 16.67%
Ovarian Epithelial Cancer Stage I (cancer is found in one or both of the ovaries): 3 people, 10.00%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 10.00%
Stable Angina (a constant chest pain): 2 people, 6.67%
Quit Smoking: 2 people, 6.67%
Non-Hodgkin's Lymphoma Unspecified Histology Indolent (malignant (cancer) cells form in the lymph system- unspecified histology indolent): 2 people, 6.67%
High Blood Cholesterol: 2 people, 6.67%
Bone Marrow Conditioning Regimen: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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