Isoptin and Dyazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isoptin (verapamil hydrochloride) and Dyazide (hydrochlorothiazide; triamterene). Common drug interactions include feeling hot among females and asthma among males.

The phase IV clinical study analyzes what interactions people have when they take Isoptin and Dyazide. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Isoptin?

Isoptin has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,539 Isoptin users. Check the latest studies of Isoptin.

What is Dyazide?

Dyazide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 11,506 Dyazide users. Check the latest studies of Dyazide.



On Jul, 04, 2026

17 people who take Isoptin and Dyazide together, and have interactions are studied.

Isoptin and Dyazide drug interactions.

What are the common drug interactions of Isoptin and Dyazide, by gender? *:

female:

  1. Feeling hot
  2. Heart rate increased
  3. Angioedema (rapid swelling of the dermis)
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Blood cholesterol increased
  6. Blood potassium decreased
  7. Diarrhoea
  8. Nausea (feeling of having an urge to vomit)
  9. Nervousness
  10. Post procedural complication

male:

  1. Asthma
  2. Eye discharge
  3. Hyperglycaemia (high blood sugar)
  4. Salivary hypersecretion (excess saliva secretion)

What are the common drug interactions of Isoptin and Dyazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Angioedema (rapid swelling of the dermis)

50-59:

n/a

60+:

  1. Abdominal pain
  2. Asthma
  3. Eye discharge
  4. Hyperglycaemia (high blood sugar)
  5. Nervousness
  6. Salivary hypersecretion (excess saliva secretion)
  7. Erythema (redness of the skin)
  8. Feeling hot
  9. Flushing (the warm, red condition of human skin)
  10. Headache (pain in head)

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 23.53%
  2. Type 2 Diabetes: 2 people, 11.76%
  3. Ill-Defined Disorder: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Isoptin and Dyazide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Isoptin and Dyazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isoptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dyazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isoptin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dyazide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on verapamil hydrochloride and hydrochlorothiazide; triamterene (the active ingredients of Isoptin and Dyazide, respectively), and Isoptin and Dyazide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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