Isoptin and Tylenol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isoptin (verapamil hydrochloride) and Tylenol (acetaminophen). Common drug interactions include ear infection fungal among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Isoptin and Tylenol. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Isoptin?

Isoptin has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,539 Isoptin users. Check the latest studies of Isoptin.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,309 Tylenol users. Check the latest studies of Tylenol.



On Jul, 12, 2026

49 people who take Isoptin and Tylenol together, and have interactions are studied.

Isoptin and Tylenol drug interactions.

What are the common drug interactions of Isoptin and Tylenol, by gender? *:

female:

  1. Ear infection fungal
  2. Epistaxis (bleed from the nose)
  3. Glossodynia (a burning or painful sensation in the tongue)
  4. Head injury
  5. Herpes virus infection
  6. Hyperhidrosis (abnormally increased sweating)
  7. Impaired healing
  8. Influenza like illness
  9. Interstitial lung disease
  10. Liver fatty (fat deposition of liver)

male:

  1. Asthenia (weakness)
  2. Bacterial infection
  3. Infusion related reaction
  4. Pneumonia
  5. Epistaxis (bleed from the nose)
  6. Overlap syndrome (an autoimmune disease of connective tissue)
  7. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  8. Disability
  9. Duodenal ulcer
  10. Oesophagitis ulcerative (inflammation of oesophagus with multiple ulcers)

What are the common drug interactions of Isoptin and Tylenol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Haemoglobin decreased
  2. Platelet count decreased
  3. Vessel puncture site haematoma (vessel puncture site swelling filled with blood)

40-49:

n/a

50-59:

  1. Heart rate increased
  2. Infusion related reaction
  3. Pneumonia
  4. Epistaxis (bleed from the nose)
  5. Overlap syndrome (an autoimmune disease of connective tissue)
  6. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  7. Disability
  8. Inflammation
  9. Lung infection
  10. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

60+:

  1. Drug ineffective
  2. Oropharyngeal pain
  3. Skin ulcer
  4. Fall
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Dry mouth
  7. Lung disorder (lung disease)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Nausea (feeling of having an urge to vomit)
  10. Dysphagia (a condition in which swallowing is difficult or painful)

What are the existing conditions these people have? *

  1. Idiopathic Pulmonary Fibrosis (chronic lung disease): 7 people, 14.29%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 12.24%
  3. Asthma: 5 people, 10.20%
  4. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 4 people, 8.16%
  5. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 8.16%
  6. Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 4 people, 8.16%
  7. Nausea (feeling of having an urge to vomit): 3 people, 6.12%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Isoptin and Tylenol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isoptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tylenol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isoptin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tylenol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on verapamil hydrochloride and acetaminophen (the active ingredients of Isoptin and Tylenol, respectively), and Isoptin and Tylenol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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