Isordil and Ranitidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isordil (isosorbide dinitrate) and Ranitidine (ranitidine). Common drug interactions include drug ineffective among females and blood pressure increased among males.

The phase IV clinical study analyzes what interactions people have when they take Isordil and Ranitidine. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Isordil?

Isordil has active ingredients of isosorbide dinitrate. eHealthMe is studying from 3,022 Isordil users. Check the latest studies of Isordil.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.



On Jul, 08, 2026

53 people who take Isordil and Ranitidine together, and have interactions are studied.

Isordil and Ranitidine drug interactions.

What are the common drug interactions of Isordil and Ranitidine, by gender? *:

female:

  1. Drug ineffective
  2. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  3. Tricuspid valve incompetence (inefficient heart valve)
  4. Asthma
  5. Hyperglycaemia (high blood sugar)
  6. Hypoglycaemia (deficiency of glucose in the bloodstream)
  7. Renal failure acute (rapid kidney dysfunction)
  8. Anaemia (lack of blood)
  9. Aortic valve incompetence
  10. Ascites (accumulation of fluid in the abdominal cavity)

male:

  1. Blood pressure increased
  2. Wheezing (a high-pitched whistling sound made while you breath)
  3. Nerve injury
  4. Colon cancer
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Dyspnoea exertional (breathlessness or shortness of breath)
  7. Injection site swelling
  8. Obstructive airways disorder (a progressive disease that makes it hard to breathe)
  9. Rales (an abnormal respiratory sound characterized by fine crackles)
  10. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

What are the common drug interactions of Isordil and Ranitidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Overdose

40-49:

  1. Arthropathy
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Abdominal pain
  4. Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
  5. Anxiety
  6. Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
  7. Arthralgia (joint pain)
  8. Asthma
  9. Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
  10. Azotaemia (excess of urea or other nitrogenous compounds in the blood)

50-59:

  1. Pericardial effusion (fluid around the heart)
  2. Cardiac tamponade (fluid accumulates in heart covering)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Rales (an abnormal respiratory sound characterized by fine crackles)
  3. Breath sounds
  4. Cardiac arrest
  5. Colon cancer
  6. Dyspnoea exertional (breathlessness or shortness of breath)
  7. Forced expiratory volume decreased (decreased lung expired air volume)
  8. Gait disturbance
  9. Hand fracture
  10. Injection site swelling

What are the existing conditions these people have? *

  1. Asthma: 11 people, 20.75%
  2. Stress And Anxiety: 7 people, 13.21%
  3. Depression: 7 people, 13.21%
  4. Nervousness: 6 people, 11.32%
  5. Insomnia (sleeplessness): 6 people, 11.32%
  6. High Blood Pressure: 5 people, 9.43%
  7. Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 5 people, 9.43%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 7.55%
  9. Coronary Artery Insufficiency (insufficiency of artery to carry blood to heart): 3 people, 5.66%
  10. Congestive Cardiomyopathy (weakening of heart muscle): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

Do you take Isordil and Ranitidine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Isordil and Ranitidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isordil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ranitidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isordil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ranitidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide dinitrate and ranitidine (the active ingredients of Isordil and Ranitidine, respectively), and Isordil and Ranitidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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