Isosorbide dinitrate and Epipen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Isosorbide dinitrate (isosorbide dinitrate) and Epipen (epinephrine). Common drug interactions include influenza like illness among females and amnesia among males.
The phase IV clinical study analyzes what interactions people have when they take Isosorbide dinitrate and Epipen. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Isosorbide dinitrate?
Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.
What is Epipen?
Epipen has active ingredients of epinephrine. It is often used in anaphylaxis. eHealthMe is studying from 23,760 Epipen users. Check the latest studies of Epipen.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
22 people who take Isosorbide dinitrate and Epipen together, and have interactions are studied.

What are the common drug interactions of Isosorbide Dinitrate and Epipen, by gender? *:
female:
- Influenza like illness
- Nausea (feeling of having an urge to vomit)
- Hypotension (abnormally low blood pressure)
- Injection site reaction
- Pain
- Pyrexia (fever)
- Body temperature fluctuation
- Chills (felling of cold)
- Chronic kidney disease
- Diarrhoea
male:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Facial bones fracture (bone fracture of face)
- Dysuria (painful or difficult urination)
- Heart rate increased
- Hyperhidrosis (abnormally increased sweating)
- Hypersensitivity
- Implant site pain
- Inflammation
- Neuropathy peripheral (surface nerve damage)
- Pneumonia
What are the common drug interactions of Isosorbide Dinitrate and Epipen, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Cardiac failure
- Pain
- Pyrexia (fever)
- Rash
- Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum)
- Upper respiratory tract infection
- Vomiting
50-59:
n/a
60+:
- Influenza like illness
- Nausea (feeling of having an urge to vomit)
- Headache (pain in head)
- Hypersensitivity
- Implant site pain
- Inflammation
- Infusion site pain
- Infusion site swelling
- Leukoplakia oral (white and gray patches inside the mouth)
- Mouth ulceration (mouth ulcers)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 27.27%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 27.27%
- Immunodeficiency Common Variable: 5 people, 22.73%
- Asthma: 5 people, 22.73%
- Hypersensitivity: 3 people, 13.64%
- Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Isosorbide dinitrate and Epipen?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Isosorbide dinitrate (13,180 reports)
- Epipen (23,760 reports)
Browse all drug interactions of Isosorbide dinitrate and Epipen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Isosorbide dinitrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Epipen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Isosorbide dinitrate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Epipen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on isosorbide dinitrate and epinephrine (the active ingredients of Isosorbide dinitrate and Epipen, respectively), and Isosorbide dinitrate and Epipen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Tylenol and Heart Rate Decreased for Women aged 60+ - 24 seconds ago
- Could Niaspan cause Hernia? - 32 seconds ago
- Drug interactions of Albuterol Sulfate and Tussionex Pennkinetic - 35 seconds ago
- Could Celecoxib cause Hemiparesis? - 45 seconds ago
- Could Profen cause Pulse Abnormal? - 48 seconds ago
- Iodine and Hypoglycemia for Women aged 60+ - a minute ago
- Iodine and Hypoglycaemia for Women aged 60+ - a minute ago
- Iodine and Insulin Shock for Women aged 60+ - a minute ago
- Iodine and Low Blood Sugar for Women aged 60+ - a minute ago
- Could Sertraline cause Malabsorption? - a minute ago