Isosorbide dinitrate and Haloperidol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isosorbide dinitrate (isosorbide dinitrate) and Haloperidol (haloperidol). Common drug interactions include blood creatine phosphokinase increased among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Isosorbide dinitrate and Haloperidol. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.

What is Haloperidol?

Haloperidol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 16,637 Haloperidol users. Check the latest studies of Haloperidol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 17, 2026

61 people who take Isosorbide dinitrate and Haloperidol together, and have interactions are studied.

Isosorbide dinitrate and Haloperidol drug interactions.

What are the common drug interactions of Isosorbide Dinitrate and Haloperidol, by gender? *:

female:

  1. Blood creatine phosphokinase increased
  2. Fungal infection
  3. Haematochezia (passage of stools containing blood)
  4. Hyperbilirubinaemia (excess of bilirubin in the blood)
  5. Peritoneal carcinoma (peritoneal cancer)
  6. Pleural effusion (water on the lungs)
  7. Pseudomonas aeruginosa infection (p. aeruginosa cause of bacterial infections of the blood)
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Respiratory failure (inadequate gas exchange by the respiratory system)
  10. Streptococcal infection

male:

  1. Anxiety
  2. Pneumonia
  3. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  4. Pain in extremity
  5. Pyrexia (fever)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Spinal osteoarthritis (joint cartilage loss in spine)
  8. Arthralgia (joint pain)
  9. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  10. Cerebral atrophy (decrement in size of brain)

What are the common drug interactions of Isosorbide Dinitrate and Haloperidol, by age (0-1 to 60+)? *:

0-1:

  1. Peripheral ischaemia (impaired circulation to an extremity)
  2. Skin necrosis (skin damage)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood creatine phosphokinase increased
  2. Hyperbilirubinaemia (excess of bilirubin in the blood)
  3. Peritoneal carcinoma (peritoneal cancer)
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. White blood cell count increased
  6. Alanine aminotransferase increased
  7. Aspartate aminotransferase increased
  8. Blood alkaline phosphatase increased
  9. Blood lactate dehydrogenase increased
  10. C-reactive protein increased

50-59:

  1. Abdominal pain
  2. Atrioventricular block complete (heart block complete)
  3. Atrioventricular block second degree (heart block second degree)
  4. Blood lactate dehydrogenase increased
  5. Blood pressure decreased
  6. Bradycardia (abnormally slow heart action)
  7. C-reactive protein increased
  8. Cardiac failure congestive
  9. Cardiogenic shock (inadequate circulation of blood)
  10. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

60+:

  1. Anxiety
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Cardiomegaly (increased size of heart than normal)
  4. Cerebral atrophy (decrement in size of brain)
  5. Electrocardiogram qt prolonged
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  8. Pain
  9. Pain in extremity
  10. Spinal osteoarthritis (joint cartilage loss in spine)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 12 people, 19.67%

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide dinitrate and Haloperidol?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Isosorbide dinitrate and Haloperidol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isosorbide dinitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Haloperidol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isosorbide dinitrate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Haloperidol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on isosorbide dinitrate and haloperidol (the active ingredients of Isosorbide dinitrate and Haloperidol, respectively), and Isosorbide dinitrate and Haloperidol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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