Isosorbide mononitrate and Aricept drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isosorbide mononitrate (isosorbide mononitrate) and Aricept (donepezil hydrochloride). Common drug interactions include electrocardiogram repolarisation abnormality among females and bradycardia among males.

The phase IV clinical study analyzes what interactions people have when they take Isosorbide mononitrate and Aricept. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

On Jul, 15, 2026

85 people who take Isosorbide mononitrate and Aricept together, and have interactions are studied.

Isosorbide mononitrate and Aricept drug interactions.

What are the common drug interactions of Isosorbide Mononitrate and Aricept, by gender? *:

female:

Electrocardiogram repolarisation abnormality
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Long qt syndrome (disorder of the heart's electrical system)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Renal failure acute (rapid kidney dysfunction)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Tremor (trembling or shaking movements in one or more parts of your body)
Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)

male:

Bradycardia (abnormally slow heart action)
Syncope (loss of consciousness with an inability to maintain postural tone)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Hallucination (an experience involving the perception of something not present)
Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Sick sinus syndrome (a collection of heart rhythm disorders)
Insomnia (sleeplessness)
Arthralgia (joint pain)

What are the common drug interactions of Isosorbide Mononitrate and Aricept, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Malaise (a feeling of general discomfort or uneasiness)
Blood pressure decreased
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dyspnoea (difficult or laboured respiration)
Herpes zoster
Infusion related reaction
Injection site reaction

50-59:

Abdominal discomfort
Ear pain
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Vomiting

60+:

Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Insomnia (sleeplessness)
Abdominal pain
Acute hepatic failure
Acute myocardial infarction (acute heart attack)
Arthralgia (joint pain)
Atrioventricular block first degree (heart block first degree)
Blood pressure decreased
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)

What are the existing conditions these people have? *

Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 22 people, 25.88%
High Blood Pressure: 16 people, 18.82%
Pain: 10 people, 11.76%
High Blood Cholesterol: 8 people, 9.41%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 9.41%
Parkinson's Disease: 8 people, 9.41%
Dementia (madness): 8 people, 9.41%
Cardiac Disorder: 7 people, 8.24%
Diabetes: 6 people, 7.06%
Stress And Anxiety: 6 people, 7.06%

* Approximation only. Some reports may have incomplete information.

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