Isosorbide mononitrate and Imuran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isosorbide mononitrate (isosorbide mononitrate) and Imuran (azathioprine). Common drug interactions include hiatus hernia among females and haemoglobin decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Isosorbide mononitrate and Imuran. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

What is Imuran?

Imuran has active ingredients of azathioprine. It is often used in crohn's disease. eHealthMe is studying from 34,915 Imuran users. Check the latest studies of Imuran.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 25, 2026

31 people who take Isosorbide mononitrate and Imuran together, and have interactions are studied.

Isosorbide mononitrate and Imuran drug interactions.

What are the common drug interactions of Isosorbide Mononitrate and Imuran, by gender? *:

female:

  1. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  2. Hyperhidrosis (abnormally increased sweating)
  3. Hypotension (abnormally low blood pressure)
  4. Knee arthroplasty
  5. Lip ulceration (ulcer of lip)
  6. Lower respiratory tract infection
  7. Lung transplant rejection (failure of lung transplant)
  8. Migraine (headache)
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Neuropathy peripheral (surface nerve damage)

male:

  1. Haemoglobin decreased
  2. Blood calcium decreased
  3. Dehydration (dryness resulting from the removal of water)
  4. Diarrhoea
  5. Drug ineffective
  6. Dyspepsia (indigestion)
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Dyspnoea (difficult or laboured respiration)
  9. Flatulence (flatus expelled through the anus)
  10. Headache (pain in head)

What are the common drug interactions of Isosorbide Mononitrate and Imuran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain upper
  2. Body temperature increased
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Cartilage injury
  5. Cough
  6. Headache (pain in head)
  7. Hyperhidrosis (abnormally increased sweating)
  8. Immune thrombocytopenic purpura (destruction of blood platelets due to the presence of antiplatelet auto antibodies)
  9. Lower respiratory tract infection
  10. Multiple injuries

50-59:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  3. Vascular rupture
  4. Vomiting
  5. Weight decreased
  6. Bowen's disease (early stage of skin cancer)
  7. Immune system disorder
  8. Back pain
  9. Cough
  10. Disability

60+:

  1. Myelofibrosis (a disease in which abnormal blood cells and fibres build up inside the bone marrow)
  2. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  3. Blood pressure systolic decreased
  4. Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells)
  5. Cellulitis (infection under the skin)
  6. Chest pain
  7. Confusional state
  8. Corneal disorder
  9. Coronary artery bypass
  10. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the existing conditions these people have? *

  1. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 7 people, 22.58%
  2. High Blood Pressure: 6 people, 19.35%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 19.35%
  4. Cardiac Disorder: 4 people, 12.90%
  5. Stress And Anxiety: 4 people, 12.90%
  6. Depression: 4 people, 12.90%
  7. Renal Disorder (kidney disease): 4 people, 12.90%
  8. Gastric Ulcer (stomach ulcer): 4 people, 12.90%
  9. Heart Attack: 3 people, 9.68%
  10. High Blood Cholesterol: 3 people, 9.68%

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide mononitrate and Imuran?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Isosorbide mononitrate and Imuran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isosorbide mononitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Imuran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isosorbide mononitrate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imuran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on isosorbide mononitrate and azathioprine (the active ingredients of Isosorbide mononitrate and Imuran, respectively), and Isosorbide mononitrate and Imuran (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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