Isosorbide mononitrate and Maxitrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isosorbide mononitrate (isosorbide mononitrate) and Maxitrol (dexamethasone; neomycin sulfate; polymyxin b sulfate). Common drug interactions include acute coronary syndrome among females.

The phase IV clinical study analyzes what interactions people have when they take Isosorbide mononitrate and Maxitrol. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

What is Maxitrol?

Maxitrol has active ingredients of dexamethasone; neomycin sulfate; polymyxin b sulfate. eHealthMe is studying from 986 Maxitrol users. Check the latest studies of Maxitrol.



On Aug, 11, 2026

15 people who take Isosorbide mononitrate and Maxitrol together, and have interactions are studied.

Isosorbide mononitrate and Maxitrol drug interactions.

What are the common drug interactions of Isosorbide Mononitrate and Maxitrol, by gender? *:

female:

  1. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  2. Acute myocardial infarction (acute heart attack)
  3. Decreased appetite
  4. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  5. Dehydration (dryness resulting from the removal of water)
  6. Diarrhoea
  7. Dyspnoea (difficult or laboured respiration)
  8. Visual acuity reduced (reduced clearness of vision)
  9. Abdominal pain
  10. Abdominal tenderness

male:

n/a

What are the common drug interactions of Isosorbide Mononitrate and Maxitrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Conjunctival erosion (removal of conjunctiva)

60+:

  1. Retinal injury (injury to retina)
  2. Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
  3. Visual acuity reduced (reduced clearness of vision)
  4. Abdominal pain
  5. Abdominal tenderness
  6. Asthenia (weakness)
  7. Atelectasis (partial or complete collapse of the lung)
  8. Blood creatinine increased
  9. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  10. Cachexia (loss of weight)

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 3 people, 20.00%
  2. Tension Headache: 3 people, 20.00%
  3. Stable Angina (a constant chest pain): 3 people, 20.00%
  4. High Blood Pressure: 3 people, 20.00%
  5. Eye Pain: 3 people, 20.00%
  6. Eye Inflammation: 3 people, 20.00%
  7. Eye Infection: 3 people, 20.00%
  8. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 3 people, 20.00%
  9. Blood Uric Acid Increased: 3 people, 20.00%
  10. Cycloplegia (paralysis of the ciliary muscle of the eye): 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide mononitrate and Maxitrol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Isosorbide mononitrate and Maxitrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isosorbide mononitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Maxitrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isosorbide mononitrate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Maxitrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide mononitrate and dexamethasone; neomycin sulfate; polymyxin b sulfate (the active ingredients of Isosorbide mononitrate and Maxitrol, respectively), and Isosorbide mononitrate and Maxitrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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