Isosorbide mononitrate and Oramorph sr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isosorbide mononitrate (isosorbide mononitrate) and Oramorph sr (morphine sulfate). Common drug interactions include blister among females and atrioventricular block complete among males.

The phase IV clinical study analyzes what interactions people have when they take Isosorbide mononitrate and Oramorph sr. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

What is Oramorph sr?

Oramorph sr has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 2,897 Oramorph sr users. Check the latest studies of Oramorph sr.

On Jul, 29, 2026

15 people who take Isosorbide mononitrate and Oramorph sr together, and have interactions are studied.

Isosorbide mononitrate and Oramorph sr drug interactions.

What are the common drug interactions of Isosorbide Mononitrate and Oramorph Sr, by gender? *:

female:

Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Dysuria (painful or difficult urination)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Mouth ulceration (mouth ulcers)
Pemphigoid (tense blisters on the skin)
Pleural effusion (water on the lungs)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Rash erythematous (redness of the skin)
Thrombocytopenia (decrease of platelets in blood)

male:

Atrioventricular block complete (heart block complete)
Bradycardia (abnormally slow heart action)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bowel movement irregularity
Delirium (wild excitement)
Diarrhoea
Drug toxicity
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematoma (collection of blood outside the blood vessels)
Hypotension (abnormally low blood pressure)

What are the common drug interactions of Isosorbide Mononitrate and Oramorph Sr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Affect lability (emotional incontinence)
Diarrhoea
Hallucination (an experience involving the perception of something not present)
Psychotic disorder
Renal failure acute (rapid kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Tremor (trembling or shaking movements in one or more parts of your body)
Vomiting

60+:

Rash erythematous (redness of the skin)
Atrioventricular block complete (heart block complete)
Drug toxicity
Dysuria (painful or difficult urination)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Hallucination (an experience involving the perception of something not present)
Metastases to spine (cancer spreads to spine)
Mouth ulceration (mouth ulcers)
Nausea (feeling of having an urge to vomit)
Neuralgia (pain in one or more nerves)

What are the existing conditions these people have? *

Neuralgia (pain in one or more nerves): 3 people, 20.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 13.33%
Weight Loss: 1 person, 6.67%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 6.67%
Type 2 Diabetes: 1 person, 6.67%
Pyoderma (any skin disease that is pyogenic): 1 person, 6.67%
Infection: 1 person, 6.67%
Gastric Ulcer (stomach ulcer): 1 person, 6.67%
Cardiac Failure: 1 person, 6.67%
Back Pain: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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