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Ivermectin and Hydroxyurea drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ivermectin (ivermectin) and Hydroxyurea (hydroxyurea). Common drug interactions include mixed liver injury among females and hypocalcaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Ivermectin and Hydroxyurea. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Ivermectin?

Ivermectin has active ingredients of ivermectin. eHealthMe is studying from 2,199 Ivermectin users. Check the latest studies of Ivermectin.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

On Jul, 15, 2026

27 people who take Ivermectin and Hydroxyurea together, and have interactions are studied.

Ivermectin and Hydroxyurea drug interactions.

What are the common drug interactions of Ivermectin and Hydroxyurea, by gender? *:

female:

  1. Mixed liver injury
  2. Dry skin
  3. Skin exfoliation (removal of the oldest dead skin cells)

male:

  1. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  2. Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
  3. Gastrointestinal toxicity (damage to digestive tract by any substance)

What are the common drug interactions of Ivermectin and Hydroxyurea, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Gastrointestinal toxicity (damage to digestive tract by any substance)

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Mixed liver injury
  2. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  3. Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
  4. Dry skin
  5. Skin exfoliation (removal of the oldest dead skin cells)

What are the existing conditions these people have? *

  1. Urinary Tract Infection: 19 people, 70.37%
  2. Pain: 18 people, 66.67%
  3. Anaemia (lack of blood): 18 people, 66.67%
  4. Primary Myelofibrosis (primary disorder of the bone marrow): 5 people, 18.52%
  5. Muscle Spasms (muscle contraction): 5 people, 18.52%
  6. Indigestion: 5 people, 18.52%
  7. Gout (uric acid crystals building up in the body): 5 people, 18.52%
  8. Diarrhea: 5 people, 18.52%
  9. Rosacea (a skin condition that causes facial redness): 3 people, 11.11%
  10. Rashes (redness): 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Ivermectin and Hydroxyurea?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ivermectin and Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ivermectin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ivermectin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyurea and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ivermectin and hydroxyurea (the active ingredients of Ivermectin and Hydroxyurea, respectively), and Ivermectin and Hydroxyurea (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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