Ivermectin and Sertraline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ivermectin (ivermectin) and Sertraline (sertraline hydrochloride). Common drug interactions include vomiting among females and furuncle among males.

The phase IV clinical study analyzes what interactions people have when they take Ivermectin and Sertraline. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Ivermectin?

Ivermectin has active ingredients of ivermectin. eHealthMe is studying from 2,199 Ivermectin users. Check the latest studies of Ivermectin.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,308 Sertraline users. Check the latest studies of Sertraline.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

18 people who take Ivermectin and Sertraline together, and have interactions are studied.

Ivermectin and Sertraline drug interactions.

What are the common drug interactions of Ivermectin and Sertraline, by gender? *:

female:

  1. Vomiting
  2. Agitation (state of anxiety or nervous excitement)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Application site erythema (redness of the skin at application site)
  5. Burning sensation
  6. Cardiovascular disorder (heart diseases)
  7. Cholesteatoma (abnormal skin growth in the middle ear behind the eardrum)
  8. Chronic kidney disease
  9. Contusion (a type of hematoma of tissue in which capillaries)
  10. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

male:

  1. Furuncle (infection of the hair follicle)
  2. Localised infection (infection at the single location)
  3. Pneumonia
  4. Rash
  5. Subcutaneous abscess

What are the common drug interactions of Ivermectin and Sertraline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Hypoxia (low oxygen in tissues)

30-39:

  1. Infection
  2. Psoriasis (immune-mediated disease that affects the skin)

40-49:

  1. Hepatitis acute
  2. Septic shock (shock due to blood infection)
  3. Nephropathy toxic (damage to kidney due to toxins)

50-59:

n/a

60+:

  1. Dehydration (dryness resulting from the removal of water)
  2. Vomiting
  3. Dizziness
  4. Enteritis (inflammation of the small intestine)
  5. Fall
  6. Hallucination, visual (seeing things that aren't there)
  7. Insomnia (sleeplessness)
  8. Mastoiditis (infection of mastoid bone)
  9. Rhinorrhoea (watery mucus discharge from the nose)
  10. Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 4 people, 22.22%
  2. Stress And Anxiety: 3 people, 16.67%
  3. High Blood Pressure: 3 people, 16.67%
  4. Sedation: 2 people, 11.11%
  5. Psoriasis (immune-mediated disease that affects the skin): 2 people, 11.11%
  6. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 11.11%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 11.11%
  8. Hypokalemia (low potassium): 2 people, 11.11%
  9. Hypertensive Crisis: 2 people, 11.11%
  10. Diabetes: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Ivermectin and Sertraline?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ivermectin and Sertraline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ivermectin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sertraline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ivermectin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sertraline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ivermectin and sertraline hydrochloride (the active ingredients of Ivermectin and Sertraline, respectively), and Ivermectin and Sertraline (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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