Ixempra kit and Aloxi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ixempra kit (ixabepilone) and Aloxi (palonosetron hydrochloride). Common drug interactions include bacterial sepsis among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Ixempra kit and Aloxi. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Ixempra kit?

Ixempra kit has active ingredients of ixabepilone. eHealthMe is studying from 991 Ixempra kit users. Check the latest studies of Ixempra kit.

What is Aloxi?

Aloxi has active ingredients of palonosetron hydrochloride. eHealthMe is studying from 9,072 Aloxi users. Check the latest studies of Aloxi.



On Jul, 16, 2026

32 people who take Ixempra kit and Aloxi together, and have interactions are studied.

Ixempra kit and Aloxi drug interactions.

What are the common drug interactions of Ixempra Kit and Aloxi, by gender? *:

female:

  1. Bacterial sepsis
  2. Diarrhoea
  3. Drug administration error
  4. Flushing (the warm, red condition of human skin)
  5. Fungaemia (fungi circulate in the blood)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Metastases to central nervous system (cancer spreads to central nervous system)
  8. Mucosal inflammation (infection of mucous membrane)
  9. Pain
  10. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

male:

  1. Acute myocardial infarction (acute heart attack)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Conduction disorder (serious disorder of the heart not responses proper to impulses)
  4. Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)

What are the common drug interactions of Ixempra Kit and Aloxi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Bacterial sepsis
  2. Fungaemia (fungi circulate in the blood)
  3. Neutropenia (an abnormally low number of neutrophils)
  4. Skin exfoliation (removal of the oldest dead skin cells)
  5. Asthenia (weakness)
  6. Back pain
  7. Dizziness
  8. Dyspnoea (difficult or laboured respiration)
  9. Erythema (redness of the skin)

40-49:

  1. Alveolitis allergic (inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts)
  2. Anxiety
  3. Constipation
  4. Flushing (the warm, red condition of human skin)
  5. Hepatic haematoma (collection of blood outside of blood vessels in liver)
  6. Malignant neoplasm progression (cancer tumour came back)
  7. Mucosal inflammation (infection of mucous membrane)
  8. Pain

50-59:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Diarrhoea
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Metastases to central nervous system (cancer spreads to central nervous system)
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  7. Agitation (state of anxiety or nervous excitement)
  8. Bone pain
  9. Candidiasis (candidiasis or thrush is a fungal infection)
  10. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

60+:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  3. Nausea (feeling of having an urge to vomit)
  4. Neuropathy peripheral (surface nerve damage)
  5. Pain
  6. Rash erythematous (redness of the skin)
  7. Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)
  8. Vomiting
  9. Acute myocardial infarction (acute heart attack)
  10. Adverse event

What are the existing conditions these people have? *

  1. Breast Cancer Metastatic: 17 people, 53.12%
  2. Breast Cancer: 12 people, 37.50%
  3. Nausea (feeling of having an urge to vomit): 4 people, 12.50%
  4. Sleep Disorder: 2 people, 6.25%
  5. Pain: 2 people, 6.25%
  6. Abdominal Pain Upper: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Ixempra kit and Aloxi?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ixempra kit and Aloxi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ixempra kit:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aloxi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ixempra kit and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aloxi and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ixabepilone and palonosetron hydrochloride (the active ingredients of Ixempra kit and Aloxi, respectively), and Ixempra kit and Aloxi (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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