Janumet and Etoposide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Janumet (metformin hydrochloride; sitagliptin phosphate) and Etoposide (etoposide). Common drug interactions include platelet count decreased among females and bacteraemia among males.

The phase IV clinical study analyzes what interactions people have when they take Janumet and Etoposide. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Janumet?

Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 25,023 Janumet users. Check the latest studies of Janumet.

What is Etoposide?

Etoposide has active ingredients of etoposide. eHealthMe is studying from 77,815 Etoposide users. Check the latest studies of Etoposide.

On Jul, 16, 2026

26 people who take Janumet and Etoposide together, and have interactions are studied.

Janumet and Etoposide drug interactions.

What are the common drug interactions of Janumet and Etoposide, by gender? *:

female:

Platelet count decreased
Pyrexia (fever)
Parotitis (inflammation of a parotid gland)
Anaemia (lack of blood)
Chest pain
Lymphadenopathy (disease or enlargement of lymph nodes)
Fatigue (feeling of tiredness)
Multi-organ failure (multisystem organ failure)
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)

male:

Bacteraemia (presence of bacteria in the blood)
Febrile neutropenia (fever with reduced white blood cells)
Flushing (the warm, red condition of human skin)
Hypotonia (low muscle tone)
Leukocytosis (increased white blood cells)
Loss of consciousness
Lung infection
Neoplasm recurrence (reoccurrence of tumour)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Oxygen saturation decreased

What are the common drug interactions of Janumet and Etoposide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Pyrexia (fever)
Parotitis (inflammation of a parotid gland)
Platelet count decreased
Anaemia (lack of blood)
Chest pain
Fatigue (feeling of tiredness)
Lymphadenopathy (disease or enlargement of lymph nodes)
Death
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Blood cholesterol increased

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Bacteraemia (presence of bacteria in the blood)
Activated partial thromboplastin time prolonged
Acute respiratory failure
Aspartate aminotransferase increased
Blood albumin decreased
Blood alkaline phosphatase increased
Blood bicarbonate increased
Blood bilirubin increased
Blood creatinine increased

What are the existing conditions these people have? *

Small Cell Lung Cancer Extensive Stage (small cell lung cancer that has spread (metastasized) to other regions of the body such as another lobe of the lung or the brain): 10 people, 38.46%
Salivary Gland Infections: 7 people, 26.92%
Lung Neoplasm Malignant (cancer tumour of lung): 5 people, 19.23%
High Blood Pressure: 4 people, 15.38%
Urination - Excessive Volume: 2 people, 7.69%
Sedation: 2 people, 7.69%
Infection: 2 people, 7.69%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 7.69%
Hyperthyroidism (over activity of the thyroid gland): 2 people, 7.69%
Fever: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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