Janumet and Exjade drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Janumet (metformin hydrochloride; sitagliptin phosphate) and Exjade (deferasirox). Common drug interactions include abdominal pain among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Janumet and Exjade. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Janumet?

Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 25,023 Janumet users. Check the latest studies of Janumet.

What is Exjade?

Exjade has active ingredients of deferasirox. It is often used in iron overload. eHealthMe is studying from 29,456 Exjade users. Check the latest studies of Exjade.

On Jul, 11, 2026

14 people who take Janumet and Exjade together, and have interactions are studied.

What are the common drug interactions of Janumet and Exjade, by gender? *:

female:

Abdominal pain
Infection
Osteoporosis (bones weak and more likely to break)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dementia (madness)
Dyspnoea (difficult or laboured respiration)
Pulmonary embolism (blockage of the main artery of the lung)
Swelling
Thrombosis (formation of a blood clot inside a blood vessel)
Adenoma benign (non-cancerous tumour -secreting)

male:

Anaemia (lack of blood)
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Electrocardiogram qt prolonged
Febrile neutropenia (fever with reduced white blood cells)
Gastric ulcer (stomach ulcer)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematuria (presence of blood in urine)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypertension (high blood pressure)
Myelodysplastic syndrome transformation (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged and gets changed into rapid progressing cancer)

What are the common drug interactions of Janumet and Exjade, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Adenoma benign (non-cancerous tumour -secreting)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Comminuted fracture (bone has broken into several pieces)
Cough
Dacryocystitis (inflammation of the lacrimal sac causing obstruction of the tube draining tears into the nose)
Drug hypersensitivity
Dysplasia (enlargement of an organ or tissue)
Foot fracture
Gastric disorder (disease of stomach)
Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)

50-59:

Abdominal pain
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)
Febrile neutropenia (fever with reduced white blood cells)
Infection
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Neutropenia (an abnormally low number of neutrophils)
Osteoporosis (bones weak and more likely to break)
Periodontitis (inflammation of the tissue around the teeth)

60+:

Anaemia (lack of blood)
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dementia (madness)
Dyspnoea (difficult or laboured respiration)
Electrocardiogram qt prolonged
Febrile neutropenia (fever with reduced white blood cells)
Gastric ulcer (stomach ulcer)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematuria (presence of blood in urine)

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 4 people, 28.57%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 21.43%
Iron Metabolism Disorder: 1 person, 7.14%
Haemochromatosis (body to absorb more iron than usual from food): 1 person, 7.14%
Blood Test Abnormal: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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