Janumet and Probiotic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Janumet (metformin hydrochloride; sitagliptin phosphate) and Probiotic (bacillus coagulans). Common drug interactions include psoriasis among females and ataxia among males.

The phase IV clinical study analyzes what interactions people have when they take Janumet and Probiotic. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Janumet?

Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 25,023 Janumet users. Check the latest studies of Janumet.

What is Probiotic?

Probiotic has active ingredients of bacillus coagulans. It is often used in irritable bowel syndrome. eHealthMe is studying from 22,461 Probiotic users. Check the latest studies of Probiotic.

On Jul, 21, 2026

47 people who take Janumet and Probiotic together, and have interactions are studied.

Janumet and Probiotic drug interactions.

What are the common drug interactions of Janumet and Probiotic, by gender? *:

female:

Psoriasis (immune-mediated disease that affects the skin)
Rectal abscess (pus in rectum)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Road traffic accident
Somnolence (a state of near-sleep, a strong desire for sleep)
Swelling
Upper-airway cough syndrome
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Urinary retention (the inability to completely or partially empty the bladder)

male:

Ataxia (loss of full control of bodily movements)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diarrhoea
Disease progression
Dizziness
Drug ineffective
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
General physical health deterioration (weak health status)

What are the common drug interactions of Janumet and Probiotic, by age (0-1 to 60+)? *:

0-1:

Abdominal discomfort
Abdominal distension
Diarrhoea
Headache (pain in head)
Swelling
Weight increased

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abnormal dreams
Anxiety
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Drug ineffective
Head discomfort
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Nausea (feeling of having an urge to vomit)
Pain
Vomiting

50-59:

Balance disorder
Blood pressure increased
Dyspnoea (difficult or laboured respiration)
Peripheral swelling
Rash
Alopecia (absence of hair from areas of the body)
Disease progression
Eye disorder
Hair colour changes
Hair disorder

60+:

Confusional state
Diarrhoea
Death
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Fall
Fatigue (feeling of tiredness)
Neuropathy peripheral (surface nerve damage)
Upper respiratory tract infection
Abdominal abscess (collection of pus in abdomen)
Abdominal discomfort

What are the existing conditions these people have? *

High Blood Cholesterol: 8 people, 17.02%
Multiple Myeloma (cancer of the plasma cells): 7 people, 14.89%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 14.89%
High Blood Pressure: 6 people, 12.77%
Type 2 Diabetes: 5 people, 10.64%
Neuropathy Peripheral (surface nerve damage): 5 people, 10.64%
Endometrial Cancer: 5 people, 10.64%
Pain: 3 people, 6.38%
Osteoporosis (bones weak and more likely to break): 3 people, 6.38%
Depression: 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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