Janumet and Rocephin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Janumet (metformin hydrochloride; sitagliptin phosphate) and Rocephin (ceftriaxone sodium). Common drug interactions include abdominal pain upper among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Janumet and Rocephin. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Janumet?

Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 25,023 Janumet users. Check the latest studies of Janumet.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

On Jul, 26, 2026

12 people who take Janumet and Rocephin together, and have interactions are studied.

What are the common drug interactions of Janumet and Rocephin, by gender? *:

female:

Abdominal pain upper
Fall
Hepatic enzyme increased
Hepatic steatosis (fatty liver disease)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Pancreatitis (inflammation of pancreas)
Post procedural haematoma (post procedural clotting of blood)
Pruritus (severe itching of the skin)
Rash
Vascular pseudoaneurysm (leakage of arterial blood from an artery into the surrounding tissue with a continuing communication between the originating artery and the resultant adjacent cavity)

male:

Abdominal pain
Aphasia (damage to the parts of the brain that control language)
Ulcer
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Cardiac failure
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Fungal infection
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Renal disorder (kidney disease)

What are the common drug interactions of Janumet and Rocephin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Renal disorder (kidney disease)

50-59:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)

60+:

Hepatic enzyme increased
Abdominal pain
Pancreatitis (inflammation of pancreas)
Post procedural haematoma (post procedural clotting of blood)
Pruritus (severe itching of the skin)
Rash
Vascular pseudoaneurysm (leakage of arterial blood from an artery into the surrounding tissue with a continuing communication between the originating artery and the resultant adjacent cavity)
Anaemia (lack of blood)
Drug hypersensitivity
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

What are the existing conditions these people have? *

Type 2 Diabetes: 5 people, 41.67%
Pain: 3 people, 25.00%
Dyspnea (difficult or laboured breathing): 3 people, 25.00%
High Blood Pressure: 3 people, 25.00%
Hypersensitivity: 2 people, 16.67%
Abdominal Pain Upper: 2 people, 16.67%
Anaesthesia: 2 people, 16.67%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 16.67%
Nausea (feeling of having an urge to vomit): 2 people, 16.67%
Abdominal Pain: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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