Janumet and Somavert drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Janumet (metformin hydrochloride; sitagliptin phosphate) and Somavert (pegvisomant). Common drug interactions include blood glucose increased among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Janumet and Somavert. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Janumet?

Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 25,023 Janumet users. Check the latest studies of Janumet.

What is Somavert?

Somavert has active ingredients of pegvisomant. eHealthMe is studying from 5,774 Somavert users. Check the latest studies of Somavert.

On Jul, 12, 2026

27 people who take Janumet and Somavert together, and have interactions are studied.

What are the common drug interactions of Janumet and Somavert, by gender? *:

female:

Blood glucose increased
Chest pain
Enzyme abnormality
Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Diarrhoea
Drug ineffective
Gallbladder disorder
Hepatitis toxic

male:

Weight decreased
Blood gonadotrophin decreased
Blood pressure fluctuation
Constipation
Dyslipidaemia (abnormal amount of lipids)
Haemoglobin increased
Hypertension (high blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)

What are the common drug interactions of Janumet and Somavert, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain upper
Diarrhoea
Gallbladder disorder
Nausea (feeling of having an urge to vomit)
Fall
Fibula fracture
Ligament rupture (tear in ligament)
Tibia fracture (fracture of lower leg bone)

40-49:

Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Drug ineffective
Injection site mass
Injection site reaction
Injection site swelling

50-59:

Blood glucose increased
Chest pain
Enzyme abnormality
Blood glucose fluctuation
Blood pressure increased
Decreased appetite
Drug ineffective
Growth hormone-producing pituitary tumour
Hypoglycaemia (deficiency of glucose in the bloodstream)
Influenza

60+:

Weight decreased
Blood gonadotrophin decreased
Blood pressure fluctuation
Constipation
Dyslipidaemia (abnormal amount of lipids)
Haemoglobin increased
Hypertension (high blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)

What are the existing conditions these people have? *

Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 25 people, 92.59%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 3 people, 11.11%
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 3 people, 11.11%
Hyperglycemia (high blood sugar): 3 people, 11.11%
Cardiac Disorder: 3 people, 11.11%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 7.41%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 2 people, 7.41%
Hypertriglyceridaemia (excess of triglycerides in the blood): 2 people, 7.41%
High Blood Cholesterol: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Janumet and Somavert?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously