Janumet and Xopenex hfa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Janumet (metformin hydrochloride; sitagliptin phosphate) and Xopenex hfa (levalbuterol tartrate). Common drug interactions include chronic kidney disease among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Janumet and Xopenex hfa. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Janumet?

Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 25,023 Janumet users. Check the latest studies of Janumet.

What is Xopenex hfa?

Xopenex hfa has active ingredients of levalbuterol tartrate. It is often used in asthma. eHealthMe is studying from 2,529 Xopenex hfa users. Check the latest studies of Xopenex hfa.



On Jul, 22, 2026

19 people who take Janumet and Xopenex hfa together, and have interactions are studied.

Janumet and Xopenex hfa drug interactions.

What are the common drug interactions of Janumet and Xopenex Hfa, by gender? *:

female:

  1. Chronic kidney disease
  2. Asthenia (weakness)
  3. Back pain
  4. Blood glucose increased
  5. Breast cancer
  6. Chest pain
  7. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  8. Cough
  9. Dyspnoea exertional (breathlessness or shortness of breath)
  10. Dysuria (painful or difficult urination)

male:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the common drug interactions of Janumet and Xopenex Hfa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease

50-59:

  1. Abdominal pain
  2. Anaemia (lack of blood)
  3. Asthenia (weakness)
  4. Back pain
  5. Blood glucose increased
  6. Chest pain
  7. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  8. Cough
  9. Dyspnoea (difficult or laboured respiration)
  10. Dyspnoea exertional (breathlessness or shortness of breath)

60+:

  1. Headache (pain in head)
  2. Abdominal pain upper
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Dyspnoea (difficult or laboured respiration)
  5. Fall
  6. Fatigue (feeling of tiredness)
  7. Pancreatic cyst
  8. Pancreatic pseudocyst (collection of tissue and fluids that forms on pancreas)
  9. Pyrexia (fever)
  10. Chronic kidney disease

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 42.11%
  2. Pain: 6 people, 31.58%
  3. High Blood Pressure: 6 people, 31.58%
  4. Type 2 Diabetes: 6 people, 31.58%
  5. Stress And Anxiety: 6 people, 31.58%
  6. Multiple Allergies (allergy to multiple agents): 5 people, 26.32%
  7. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 21.05%
  8. Motion Sickness (travel sickness): 4 people, 21.05%
  9. Muscle Aches (muscle pain): 4 people, 21.05%
  10. Depression: 4 people, 21.05%

* Approximation only. Some reports may have incomplete information.

Do you take Janumet and Xopenex hfa?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Janumet and Xopenex hfa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Janumet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xopenex hfa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Janumet and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xopenex hfa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride; sitagliptin phosphate and levalbuterol tartrate (the active ingredients of Janumet and Xopenex hfa, respectively), and Janumet and Xopenex hfa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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