Januvia and Azor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Januvia (sitagliptin phosphate) and Azor (amlodipine besylate; olmesartan medoxomil). Common drug interactions include blood glucose increased among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Januvia and Azor. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Januvia?

Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 72,818 Januvia users. Check the latest studies of Januvia.

What is Azor?

Azor has active ingredients of amlodipine besylate; olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 3,922 Azor users. Check the latest studies of Azor.

On Jul, 19, 2026

48 people who take Januvia and Azor together, and have interactions are studied.

What are the common drug interactions of Januvia and Azor, by gender? *:

female:

Blood glucose increased
Drug ineffective
Chronic kidney disease
Dizziness
Abdominal discomfort
Constipation
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

male:

Renal failure (kidney dysfunction)
Chronic kidney disease
Blood creatinine increased
Blood glucose increased
Burning sensation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Death
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Dysuria (painful or difficult urination)
Erythema (redness of the skin)

What are the common drug interactions of Januvia and Azor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pancreatitis (inflammation of pancreas)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Arterial thrombosis (formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system)
Burning sensation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Dyspnoea (difficult or laboured respiration)
Hospitalisation

60+:

Blood glucose increased
Drug ineffective
Blood pressure decreased
Depressed level of consciousness
Dysphagia (a condition in which swallowing is difficult or painful)
Rales (an abnormal respiratory sound characterized by fine crackles)
Sepsis (a severe blood infection that can lead to organ failure and death)
Asthenia (weakness)
Blood creatinine increased
Death

What are the existing conditions these people have? *

Type 2 Diabetes: 11 people, 22.92%
High Blood Cholesterol: 7 people, 14.58%
Pain: 5 people, 10.42%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 10.42%
Blood Glucose Increased: 5 people, 10.42%
Neuralgia (pain in one or more nerves): 3 people, 6.25%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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