Januvia and Chlorhexidine gluconate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Januvia (sitagliptin phosphate) and Chlorhexidine gluconate (chlorhexidine gluconate). Common drug interactions include drug ineffective among females and blood glucose increased among males.

The phase IV clinical study analyzes what interactions people have when they take Januvia and Chlorhexidine gluconate. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Januvia?

Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 72,818 Januvia users. Check the latest studies of Januvia.

What is Chlorhexidine gluconate?

Chlorhexidine gluconate has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 8,233 Chlorhexidine gluconate users. Check the latest studies of Chlorhexidine gluconate.

On Jul, 12, 2026

30 people who take Januvia and Chlorhexidine gluconate together, and have interactions are studied.

Januvia and Chlorhexidine gluconate drug interactions.

What are the common drug interactions of Januvia and Chlorhexidine Gluconate, by gender? *:

female:

Drug ineffective
Dry eye (lack of adequate tears)
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea (difficult or laboured respiration)
Ear pain
Eosinophil count decreased
Gait disturbance
Gastric mucosal lesion (lesion of stomach mucous membrane)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gingivitis (inflammation of gums)

male:

Blood glucose increased
Thrombosis (formation of a blood clot inside a blood vessel)
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Death
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dizziness
Epistaxis (bleed from the nose)

What are the common drug interactions of Januvia and Chlorhexidine Gluconate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Influenza
Oropharyngeal pain
Speech disorder

50-59:

n/a

60+:

Bone loss
Cardiomegaly (increased size of heart than normal)
Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
Osteonecrosis of jaw (death of bone of jaw)
Ovarian cyst (fluid filled sac of the ovary)
Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Quality of life decreased
Road traffic accident
Tooth loss

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 20.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 16.67%
Pain: 5 people, 16.67%
Metastases To Bone (cancer spreads to bone): 4 people, 13.33%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 10.00%
Sinus Congestion (blockage of sinus): 2 people, 6.67%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 6.67%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 6.67%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 6.67%
Cough: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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