Januvia and Copegus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Januvia (sitagliptin phosphate) and Copegus (ribavirin). Common drug interactions include rash among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Januvia and Copegus. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Januvia?

Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 72,818 Januvia users. Check the latest studies of Januvia.

What is Copegus?

Copegus has active ingredients of ribavirin. It is often used in hepatitis c. eHealthMe is studying from 15,115 Copegus users. Check the latest studies of Copegus.



On Jul, 19, 2026

35 people who take Januvia and Copegus together, and have interactions are studied.

Januvia and Copegus drug interactions.

What are the common drug interactions of Januvia and Copegus, by gender? *:

female:

  1. Rash
  2. Vertigo
  3. Dyspnoea (difficult or laboured respiration)
  4. Platelet count decreased
  5. Pyrexia (fever)
  6. Renal failure acute (rapid kidney dysfunction)
  7. Visual impairment
  8. Anaemia (lack of blood)
  9. Decreased appetite
  10. Dehydration (dryness resulting from the removal of water)

male:

  1. Rash
  2. Muscular weakness (muscle weakness)
  3. Cardiac tamponade (fluid accumulates in heart covering)
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Oedema (fluid collection in tissue)
  6. Pericardial haemorrhage (bleeding into the heart)
  7. Pericarditis (inflammation of the pericardium)
  8. Arthralgia (joint pain)
  9. Decreased appetite
  10. Depression

What are the common drug interactions of Januvia and Copegus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Muscular weakness (muscle weakness)
  2. Hypoaesthesia (reduced sense of touch or sensation)
  3. Rash
  4. Arthralgia (joint pain)
  5. Decreased appetite
  6. Depression
  7. Glomerulonephropathy (any noninflammatory disease of the renal glomeruli)
  8. Leukopenia (less number of white blood cells in blood)
  9. Myalgia (muscle pain)
  10. Neutropenia (an abnormally low number of neutrophils)

50-59:

  1. Blood bilirubin unconjugated increased
  2. Gastric varices haemorrhage (dilated submucosal veins in the stomach with bleeding)
  3. Haematemesis (vomiting of blood)
  4. Haemoglobin decreased
  5. Abdominal pain
  6. Chest pain
  7. Cough
  8. Depression
  9. Dizziness postural
  10. Dyspnoea (difficult or laboured respiration)

60+:

  1. Rash
  2. Anaemia (lack of blood)
  3. Oedema (fluid collection in tissue)
  4. Pericardial haemorrhage (bleeding into the heart)
  5. Pericarditis (inflammation of the pericardium)
  6. Vertigo
  7. Colon cancer
  8. Platelet count decreased
  9. Pyrexia (fever)
  10. Visual impairment

What are the existing conditions these people have? *

  1. High Blood Pressure: 5 people, 14.29%
  2. Type 2 Diabetes: 4 people, 11.43%

* Approximation only. Some reports may have incomplete information.

Do you take Januvia and Copegus?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Januvia and Copegus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Januvia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Copegus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Januvia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Copegus and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sitagliptin phosphate and ribavirin (the active ingredients of Januvia and Copegus, respectively), and Januvia and Copegus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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